血蓝蛋白模型化合物的合成和性质  

Synthesis and Properties of Hemocyanin Model Compounds

作　　者：冯清[1] 张树森[1] 何永言[1] 石巨恩[2] 

机构地区：[1]同济医科大学基础医学院化学教研室,武汉430030 [2]华中师范大学化学系无机组,武汉430070

出　　处：《同济医科大学学报》1996年第3期199-202,共4页Acta Universitatis Medicinae Tongji

基　　金：国家自然科学基金资助项目(NO.28970014)

摘　　要：合成N,N,N^1,N^1-四(2-苯并咪唑基甲基)丁二酰胺(SDB)及Cu(Ⅰ)双核配合物,测定了红外光谱(IR)、电子光谱(UV/VIS)、电子顺磁共振谱(ESR)、电导、元素分析和循环伏安图(CV).UV/VIS谱和 CV图表明Cu(Ⅰ)配合物具有氧合作用,氧加合物的UV/VIS谱(570 um的ε_m=890 L·mol^(-1)·cm^(-1),355nm的ε_m=16 637 L·mol^(-1)·cm^(-1)),与氧合血蓝蛋白相近,产物〔(Cu_2(SDB)O_2(CIO_4)_2·3H_2O的分离进一步证明了氧加合物的存在.A new dinucleating ligand N,N,N',N' -tetrakis (2-benzimidazolylmethyl)-1, 4-malonyl diamide and dicopper (I) complex was prepared. The 'HNMR,IR, UV/VIS, ESR, conductivities, elemental analysis and cyclic voltamograms of these complexes were determined. The UV/VIS and CV spectra showed that Cu(I) had the reaction to oxygen of hemocyanin and that the dioxygen adduct had the charge transfer bands 570 nm, 355 nm which are similar to those of oxyhemocyanin. The dioxygen adduct [Cu2(SDB)O2)](ClO4)2·3H2O could be isolated from the solution.

关 键 词：双核配合物 氧合作用 血蓝蛋白 Cu(I)离子 

分 类 号：Q510.2[生物学—生物化学]