慢性阻塞性肺疾病支气管舒张试验误差原因分析  

Causative analysis of errors in bronchodiastolic test for chronic obstructive pulmonary disease

作　　者：陈明[1] 代秀梅[1] 

机构地区：[1]安徽省蚌埠市第四人民医院呼吸内科,233010

出　　处：《淮海医药》2006年第3期185-186,共2页Journal of Huaihai Medicine

摘　　要：目的分析慢性阻塞性肺疾病(COPD)患者支气管舒张试验误差的原因。方法选择165例具有气流阻塞症状的COPD患者和支气管哮喘患者做支气管舒张试验,分别测定吸入支气管扩张剂前、后的用力呼气量(FVC)及第1秒用力呼气量(FEV1)并统计。结果90.7%支气管哮喘患者使用支气管扩张剂后,肺功能明显改善,说明气流阻塞可逆程度较大,意义显著(P<0.01);COPD患者试验后仅8.7%肺功能明显改善,91.3%支气管舒张试验阴性,气流阻塞可逆程度小,变异性也小,无意义(P>0.05)。结论大部分COPD患者吸入支气管扩张剂后,肺功能应有所改善[1,2],但因COPD患者气道的病理特点,外界因素及复杂的临床过程,造成试验结果与理论有差异。Objective To analyze errors in bronchodiastolic test for sufferers of chronic obstructive pulmonary disease （COPD）. Methods 165 cases of COPD and bronchial asthma symptomatic of air flow obstruction were selected and given bronchodiastolic test. Forced vital capacity （FVC） and first second of forced expiratory volume （FEV1） before and after the inhalation of bronchial expander were measured and counted up. Results 90.7% of sufferers of bronchial asthma improved a lot in their pulmonary function after using the bronchial expander, which indicated that to a great extent the air flow obstruction is significantly reversable （P 〈 0.01）. On the other nand, only 8.7% of COPD patients showed improvement of pulmonary funetion after the test. 91.3% of them were negative in the bronchodiastolic test with low level reversable air flow obstruction and variation, which signifies little statistic significance （P 〉 0.05）. Conclusion The pulmonary function of most COPD patients should be turned for better after the application of bronchial expander. The difference between theory and the test result may be attributed to the collective effects of pathological features of COPD sufferers＇ gas passage, external factors and complicated clinical process.

关 键 词：肺疾病 慢性阻塞性 哮喘 支气管舒张试验 

分 类 号：R563[医药卫生—呼吸系统]