不稳定性心绞痛患者血清cTnI、CK-MB的检测结果分析  

Analysis of cTnI and CK-MB and prognosis of unstable angina pectoris

作　　者：陶黎岚[1] 王清云[1] 

机构地区：[1]安徽省蚌埠市第一人民医院检验科,233000

出　　处：《淮海医药》2006年第3期195-196,共2页Journal of Huaihai Medicine

摘　　要：目的观察肌钙蛋白(cTnI)水平与不稳定型心绞痛(UAP)患者的相关性。方法分别采用ELISA、免疫抑制法检测33例UAP患者血清cTnI、磷酸肌酸同工酶(CK-MB)的含量,分析其一般临床特征,同期检测20例健康体检者为对照组。结果33例UAP患者中有16例cTnI增高,与正常对照组比较差异有非常显著性(P<0.01),CK-MB差异无显著性(P>0.05)。结论cTnI增高是发生不稳定性心绞痛的独立危险因素,亦是判断患者预后的重要生化指标。Objective To observe the relationship between the serum cTnI content and the prognosis in patients with unstable angina pectoris （UAP）. Methods Serum cTnI and CK-MB level of 33 UAP patients were determined and the clinical features analysed. Results In the 33 UAP patients, 16 patients had an elevated serum cTnI level, which was significantly higher in the UAP group than in the control group （P 〈 0.01）. The CK-MB was not different from that in the control group （P 〉 0.05）, cTnI level was an independent risk factor to cardiac event. Conclusion Serum cTnI level is an important biochemical indicator of the risk grading and prognosis of UAP patients.

关 键 词：心绞痛 不稳定型 肌钙蛋白Ⅰ 预后 

分 类 号：R541.42[医药卫生—心血管疾病]