宣导泻肺饮治疗慢性心力衰竭的临床研究  

Clinical Study of Xuandaoxiefeiyin for Chronic Heart Failure

作　　者：杨祥坤[1] 张莉莉[1] 华新宇[2] 许国振[1] 朱浩[1] 贺劲[1] 王琴[1] 

机构地区：[1]湖北省武汉市中医医院 [2]湖北中医学院2003级

出　　处：《中西医结合心脑血管病杂志》2006年第6期471-473,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：武汉市卫生局基金资助项目[No.武卫(2003)228号]

摘　　要：目的观察中药宣导泻肺饮治疗慢性心力衰竭的疗效及对心功能的影响.方法将心功能Ⅲ级～Ⅳ级,辨证属三焦壅塞、痰瘀水停证病人96例随机分为治疗组（48例）和对照组（48例）,对照组采用西药常规治疗,治疗组在此基础上加用宣导泻肺饮,两组疗程均为8周.结果两组治疗后在中医证候、Lee氏心力衰竭记分以及心功能NYHA分级、左室射血分数（LVEF）、短轴缩短率（FS）、左室收缩末容积（LVESV）均比治疗前有明显改善（P〈0.01）,但治疗组疗效优于对照组（P＜0.05）;治疗组治疗后左室舒张末容积（LVEDV）较治疗前也有明显改善（P〈0.01）;治疗组利尿剂和地高辛用量以及住院天数明显少于对照组（P〈0.05或P〈0.01）.结论宣导泻肺饮结合常规西药治疗心力衰竭,可减少住院天数,减少利尿剂和地高辛的用量,改善心功能和提高临床疗效.Objective To observe the therapeutic effect of Xuandaoxiefeiyin （XDXFY）on chronic heart failure（CHF）. Methods Ninety - six patients （pts） with CHF （NYHA Ill or IV ） of syndrome of Sanjiao obstruction, phlegm and blood stasis and fluid - retention were divided into two groups randomly： Treatment group （ n = 48） and control group （ n = 48）. pts in control group were treated by routine treatment（diuretic, ACEI, digoxin）. Pts in treatment group were treated by XDXFY with routine treatment. Results Following the treatment, the symptoms of traditional Chinese medicine, Lee＇s mark of CHF and the NYHA classification had distinctly improved than that in pre - treatment in both groups（ P 〈 0.01 ）. The improvement in treatment group was significantly superior to the control group（ P 〈 0.05）. Compared with pre - treatment, LVEF, FS, LVESV were improved significantly in both groups（P〈0.01）. The effects in the treatment group were better than that in control group （P 〈 0.01 ）. LVEDV in treatment group was improved distinctly comparing with pretreatment（ P 〈 0.05 or P 〈 0.01 ）. Conclusion XDXFY with routine treatment could reduce the use of digoxin and diuretic and the stay in hospital, strengthen the therapeutic effect and improve heart function.

关 键 词：心力衰竭 慢性 心功能 宣导泻肺饮 

分 类 号：R259[医药卫生—中西医结合]