光致变色剂5－甲基螺噁嗪的改良合成  

An Improved Synthesis of the Photochromic 5-Methylspirooxazine

作　　者：南志祥[1] 李春荣[1] 董绮功[1] 李仲杰[1] 

机构地区：[1]西北大学化学系

出　　处：《西北大学学报（自然科学版）》1996年第3期231-234,共4页Journal of Northwest University（Natural Science Edition）

基　　金：陕西省自然科学基金

摘　　要：报道了先致变色剂５－甲基螺嗪的改良合成，关键中间体２，３，３，５－四甲基－３Ｈ－吲哚由相应芳胺经Ｍｏｈｌａｕ－Ｂｉｓｈｌｅｒ反应制备。所需原料３－溴－３－甲基－２－丁酮由相应酮在四氯化碳中，无催化剂条件下与溴反应制得。改进了由５－甲基费歇尔碱和１－亚硝基－２－萘酚制备目标分子的操作方法，对有关反应机理进行了探讨并研制出光致变色油墨。An efficient synthesis of the photochromic 5-methyl-spirooxazine is reported.2, 3, 3, 5-Tetramethyl-3H-indole, as a key intermediate for this synthesis is prepared by the Mohlau-Bischerreaction between 4-methyl aniline and 3-bromo-3-methyl-2-butanone, which start from the bromationof the corresponding ketone in CCl4 and the absence of catalyst. The modified procedure is describedfor the condensation cyclization of 5-methyl-Fisher k base and 1-nitroso-2-naphthol. The mechamismsof relative reactions are proposed and a photochromic ink is formulated.

关 键 词：甲基螺恶嗪 油墨 光致变色剂 合成 

分 类 号：TQ251.3[化学工程—有机化工] TQ638