冬虫夏草人工菌丝对卷烟烟雾诱发遗传损伤的保护作用  

Protective Effects of Cordyceps Sinensis(Berk) Sacc, Artificial Pypha on Geneyic Damage Induced by Cigarette Smoke

作　　者：马继霞[1] 毕诗秀 

机构地区：[1]北京大学生命科学学院

出　　处：《北京大学学报（自然科学版）》1996年第4期521-526,共6页Acta Scientiarum Naturalium Universitatis Pekinensis

摘　　要：以微核试验和精子畸形试验为指标，评价冬虫夏草人工菌丝对卷烟烟雾诱发小鼠遗传物质损伤的保护作用。结果表明，卷烟烟雾处理１，２及４周的各组，均显示潜在的遗传毒性。冬虫夏草具有明显的保护作用，两周的抑制率可达５５％。两个烟雾处理组间，精子畸形百分率无显著性差异（Ｐ＞０．０５）。By means of micronucleus test of bone marrow cell and sperm malformyion test, the protective effects of the Cordyceps sinensis(Berk) Sacc, artificial pypha on genetic damage induced by cigarette smoke was studied in Kunming mice stain. The results show that mutagenic potential in groups treated with cigarette smoke for 1, 2 and 4 weeks was noticed. The antimutation function of the Cordyceps sinensis (Berk) Sacc, artificial pypha is very evident in groups for 2 weeks. The rate of suppression micronucleus is 55%. No significant difference was found among the percentage of sperm malformtion of two treating groups ( P>0.05 ).

关 键 词：冬虫夏草 人工菌丝 卷烟 烟雾 遗传损伤 保护 

分 类 号：R282.710.5[医药卫生—中药学]