微波辐射溶剂回流法提取石蒜中石蒜碱、力可拉敏和加兰他敏  

Post-Microwave-Irradiated Reflux Extraction of Lycorine, Lycoramine and Galanthamine from Lycoris Radiata

作　　者：范华均[1] 肖小华[1] 刘玉竹[1] 李攻科[1] 

机构地区：[1]中山大学化学与化学工程学院,广东广州510275

出　　处：《中山大学学报（自然科学版）》2006年第3期46-49,53,共5页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：国家自然科学基金资助项目(20375050);国家重点基础研究发展规划资助项目(G2000026302)

摘　　要：采用微波辐射溶剂回流提取法(PM IRE)提取石蒜中的石蒜碱、力可拉敏和加兰他敏生物碱,研究了微波功率、辐射时间等因素对生物碱提取率的影响,比较了传统溶剂回流法(SRE)和密闭微波辅助提取法(CMAE)对生物碱的提取率。结果表明,采用PM IRE法后3种生物碱的提取率明显提高,样品放大提取试验结果令人满意。方法简单,操作方便。采用电子扫描显微镜(ESM)观察样品表面结构,发现微波辐射后石蒜细胞发生了破壁。A new method of extraction of lycorine, lycoramine and galanthamine from the lycoris radiata with the post-microwave-irradiated reflux extraction （PMIRE） has been developed. Factors such as solvent, microwave power, content of water, temperature and time and so on were studied in detail. A comparison among PMIRE, the conventional solvent reflux extraction （SRE） and the closed microwave-assisted extraction （CMAE） was made for the yields of 3 alkaloids. With the help of electron scan microscope, the cell-rupture on the surfaces of the plant has been found after microwave irradiation.

关 键 词：石蒜 微波辐射溶剂提取 石蒜碱 力可拉敏 加兰他敏 

分 类 号：O657.7[理学—分析化学]