78例儿童孤独症患者体感诱发电位分析  

Analysis of SEP in 78 children with infantile autism

作　　者：古美华[1] 陶细姣[1] 蓝莉玲[1] 高文芳[2] 杨志伟[3] 卢建平[3] 

机构地区：[1]深圳市第一人民医院内科肌电图室,广东深圳518020 [2]深圳市第八人民医院肌电图室 [3]深圳市康宁医院

出　　处：《临床神经电生理学杂志》2006年第3期150-151,154,共3页Journal of Clinical Electroneurophysiology

摘　　要：目的:通过观察和分析儿童孤独症患者体感诱发电位(SEP)的改变,探讨其在儿童孤独症诊断中的临床意义。方法:对1岁零8个月至8岁的78例孤独症儿童进行SEP检查,观察皮层第一个电位P40潜伏期及P40、N50、P60、N75波幅的改变。结果:78例孤独症患儿皮层电位P40潜伏期均有延长,其中双侧延长55例,单侧延长23例,并波幅分化差或左右不对称18例。结论:孤独症患者体感传导通路皮层电位潜伏期延长和波幅的改变,提示皮层下(包括脑干、丘脑)和相关皮层功能受损的可能,结合影像学检查,对评价神经系统功能及预后有一定的价值,对孤独症患儿临床诊断有帮助。Objective：To explore the clinical value of somatosensory evoked potential （SEP） in the diagnosis of infantile autism. Methods： The SEP was performed in 78 children with infants autism,so as to observe the change of the latency and amplitude of cortex potential P40, N50,P60, N75. of SEP. Resuits： The cortex potential of children with infantile autism showed prolonged latency, and the amplitudes of both sides were asymmetrical. Conclusion：The extension of latency of cortex potential of children with infantile autism suggests the possibility of functional damage from spinal cord to brain stem and of cortex, and there exists some value to evaluate the function of nerve system and prognosis of infantile autism.

关 键 词：孤独症 体感诱发电位 儿童 

分 类 号：R729[医药卫生—儿科] R741.044[医药卫生—临床医学]