光学活性氨基醇类配体的合成  

Synthesis of Opitcally Active Amino Alcohol Ligands

作　　者：黄兴兰[1] 刘全忠[1] 郭川胜[1] 王振雷[1] 

机构地区：[1]西华师范大学化学化工学院,四川南充637002

出　　处：《西华师范大学学报（自然科学版）》2006年第2期158-160,共3页Journal of China West Normal University(Natural Sciences)

摘　　要：光学纯的(S)-联二萘酚与三氟甲基磺酸酐反应生成三氟甲基磺酸酯,在无水条件下与甲基格氏试剂完成Kum ada偶联反应,进而溴代生成二溴化物3,二溴化物3与氨基醇作用得到以联二萘酚衍生的氨基醇配体.Optically pure 1,1′-binaphthalene-2,2′-diol（BINOL） was first reacted with triflic anhydrine to yield the rifluromethanesufonic esters, which was coupled with methlmagnesium iodides under Kumada catalyzed conditions to afford the 2,2′-dimethyl-1,1′-binaphthalene. Submission of the compound to bromination and sequentially the reaction with chial aminol alcohols under reflux with acetonitrile as the solvent gave optically pure BINOL derived from amino alcohols.

关 键 词：(S)-联二萘酚 1 2-二苯基氨基醇 合成 

分 类 号：O626.1[理学—有机化学]