机构地区:[1]山东大学临床医学院 [2]济南市中心医院院内感染办公室,山东省济南市250013 [3]济南市中心医院社区卫生服务中心,山东省济南市250013
出 处:《中国临床康复》2006年第24期167-169,共3页Chinese Journal of Clinical Rehabilitation
摘 要:背景:近年来,早产儿的存活率逐年上升,但由于早产儿大脑发育不成熟,智能发育往往较正常儿落后。目的:探讨以家庭为中心,以物质营养、信息刺激和爱抚为主要干预内容的早期干预对早产儿婴儿期智能发育水平的影响。设计:随机抽样对照观察。单位:山东大学临床医学院·济南市中心医院儿科。对象:选择2000-05/2002-07在济南市中心医院出生的孕31~36周早产儿35例(男18例,女17例)作为早期干预对象,同时设立同期出生的孕31~36周早产儿33例(男18例,女15例)和足月新生儿49例(男26例,女23例)为对照组。方法:以家庭为中心,以营养、信息刺激和爱抚为主要干预内容进行早产儿早期干预,建立健康档案,进行抚触和穴位按摩,1个月内家访2次;两对照组只在3,6,10月龄常规体检一次。在10月龄时采用Gesell发育诊断量表和日本S~M社会生活能力量表对各组婴儿的智能发育水平进行评定。主要观察指标:各组婴儿智能发育水平评定结果。结果:在实验过程中,早产儿干预组死亡1例,失访2例,合格病例32例,合格率91%。早产儿对照组33例,失访3例,合格病例30例,合格率91%。足月儿对照组49例,失访3例,合格病例46例,合格率94%。①早产儿干预组10月龄时Gesell各能区的发育商DQ及日本S~M社会生活能力评定值均显著高于早产儿对照组,其中适应性、精细动作、语言、个人社会行为4项发育商差异具有高度显著性意义。②早产儿干预组10月龄时Gesell各能区的发育商DQ及日本S~M社会生活能力评定值均低于足月儿对照组,差异有显著性意义。③干预组中胎龄大于35周的早产儿各评定值均低于足月儿对照组,但差异无显著性意义(P>0.05)。结论:早期干预对早产儿婴儿期智能发育有明显的促进作用,部分早产儿经干预可达到足月儿水平。BACKGROUND: Recently, the survival rate of premature infants increases year by year, but the cerebral growth of premature infants is immature, so the intellectual development of premature infants is slower than that of normal infants. OBJECTIVE: To explore the effect of family-orlented early intervention, which took material nutrition, information stimulation and petting as main interventional content, on level of intellectual development in premature infants in infantile age. DESIGN: Randomized sampling controlled observation. SETTING: Department of Pediatrics, Clinical Medical College of Shandong University.Jinan Central Hospital. PARTICIPANTS: Totally 35 premature infants of 31-36 weeks (18 males and 17 females) were enrolled as early interventional subjects, who were born at Jinan Municipal Central Hospital between May 2000 and July 2002. Meanwhile, 33 premature infants of 31-36 weeks (18 males and 15 females) born in the same period and 49 mature neonates (26 males and 23 females) were enrolled in control group. METHODS: The family-oriented early intervention, which considered nutrition, information stimulation and petting as chief interventional content, were performed in premature infants, and health archives was established. Taction and point massage were conducted. Home visit was done twice in one month. One routine health examination was determined at 3, 6 and 10 months in the two control groups. The level of intellectual development was assessed in infants of 10-month old of each group with C, esell Develop- mental Schedules (GDS) and Japanese S-M Social Living Ability Scale. MAIN OUTCOME MEASURES: Evaluation of level of intellectual development in infants of each group. RESULTS: In the premature interventional group, 1 premature infant died, 2 withdrew from the study, and 32 eligible cases with the eligible rate of 91.4%; Among the 33 premature infants in the premature control group, there were 3 withdrawing from the study, and 30 eligible cases with the eligi
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