用钴卟啉修饰电极催化测定多巴胺等神经递质  

Determination of Catechols on the Modified Electrotle by Electrocatalytic Oxidation

作　　者：钱江红[1] 刘海鹰[1] 邓家祺[1] 

机构地区：[1]复旦大学化学系

出　　处：《生物化学与生物物理进展》1996年第1期73-76,共4页Progress In Biochemistry and Biophysics

基　　金：国家自然科学基金;长春应用化学研究所电分析开放实验室资助

摘　　要：将５，１０，１５，２０－四－（３－甲氧基－４－羟基苯基）卟啉钴（ＣｏＴＭＨＰＰ）修饰在玻碳电极表面，制备成对多巴胶等神经递质有高灵敏度响应的ＣＯＴＭＨＰＰ修饰电极．电极具有灵敏度高、响应快、稳定性好等特点．电极响应时间小于１０ｓ，儿茶酚类化合物的检测浓度为１０（－６）ｍｏｌ／Ｌ．The 5, 10, 15, 20-tetrakis (3methoxy-hydroxyphenyl) porphyrin cobalt is absorbed on the surface of the glassy carbon electrode to make a CoTMHPP modified electrode.The modified electrode has high sensitivity and good electrocatalytic oxidation towards catechols for each range of their responses, and the response time is less than 10 s. The electrode possesses characteristicsof high catalytic activity, fast response, goodstability and a long lifetime under the optimal operations.

关 键 词：神经递质 多巴胺 钴卟啉 修饰电极 

分 类 号：R338[医药卫生—人体生理学]