慢性乙型肝炎合并脂肪肝与血脂的相关性分析  

Analysis of the relation between chronic hepatitis combined fatty liver and the lever of blood lipid

作　　者：王波 徐风 王欣 谢风[3] 

机构地区：[1]大连市第六人民医院检验科,辽宁大连116001 [2]大连市金州区第一人民医院 [3]吉林大学中日联谊医院

出　　处：《中国实验诊断学》2006年第6期628-630,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的对慢性乙型肝炎合并脂肪肝与血脂之间关系进行分析。方法采用超声和酶法,检测患者脂肪肝和血脂水平。结果124例乙型肝炎合并脂肪肝组及264例正常脂肪肝组,CHOL、TG、LDL-C水平较正常对照组均有显著升高(P<0.001),但升高程度有差异。其中正常脂肪肝组CHOL、TG升高最为明显,慢性乙型肝炎合并脂肪肝组LDL-C水平升高最为明显。慢性乙型肝炎合并脂肪肝组HDL-C水平明显下降(P<0.001),正常脂肪肝组HDL-C水平明显升高(P<0.01)。慢性乙型肝炎合并脂肪肝患者血脂变化以LDL-C增高(84.67%),单纯TG增高(41.93%),HDL-C降低(58.87%)为主要表现。结论慢性乙型肝炎合并脂肪肝与高TG、LDL-C增高、HDL-C降低有密切的关系。Objective To investigate the relation between chronic hepatitis combined fatty liver and the level of blood lipid. Methods Using the method by ultrasonography examined fatty liver,and to detect CHOL,TG, LDL-C, HDL-C by Olympas Automatic Biochemical Analyzer. Results To select 124chronic hepatiis combined fatty liver patients as a test group 1 and to select 264 simple fatty liver patients as test group 2,The levels of serum CHOL,TG, LDL-C in test groups were significantly higher than those in health control （ P 〈 0.001） .The levels of serum CHOL,TG in test group 2 were increased move markedly. The level of serum LDL-C in test group 1 was increased more markedly.The level of serum HDL-C in test group 1 was significantly lower than those d health control respectively （ P 〈 0.001）.The level of serum HDL-C in test group 2 was significantly higher than those of health control respecfively （P〈 0.01）. It is the main variations that chronic hepatitis combined fatty liver patients have high CHOL （84.67%）, high TG （41.93%）and low HDL-C （58.87%）. Conclusion There is high relativity in the production of the chronic hepatitis combined fatty liver and the increase of TG,LDL-C the decrease of HDL-C.

关 键 词：慢性乙型肝炎 脂肪肝 血脂 总胆固醇(CHOL) 甘油三脂(TG) 低密度脂蛋白胆固醇(LDL-C) 高密度脂 蛋白胆固醇(HDL-C) 

分 类 号：R512.62[医药卫生—内科学] R575.5[医药卫生—临床医学]