血清胱抑素C在评价糖尿病患者早期肾损伤中的价值  

Diagnostic value of serum cystain-C in evaluating early stage damage in kidney of diabetes patient

作　　者：董梅[1] 孟祥红[1] 佟爱华[1] 李艳艳[1] 吴纯[1] 

机构地区：[1]解放军总医院第309临床部,北京100091

出　　处：《中国实验诊断学》2006年第6期642-643,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的糖尿病患者血中Cys-c浓度变化,来探讨其在糖尿病患者早期肾损伤中的价值。方法使用德灵BNⅡ特种蛋白仪采用免疫透射比浊法测定Cys-c浓度。结果血清中Cys-c浓度变化趋势与血清中Scr相同,呈显著相关(r=0.845,r=0.723),阳性似然比(+LR)为5,阴性似然比(-LR)为0。结论血清胱抑素C可作为评估肾移植受者早期肾功损害的敏感指标。Objective To deraonstrate the diagnostic value of serum Cys-c in evaluating early stage damage in kideny of diabetes patient.Methods particle-enhanced immunonelometry on the Behring nephelometer systems（BNⅡ ）.Results There was a signifrcant positive correlation between Cys-c and creatinine level（ r = 0.845）.Masculine gender however compare（ ＋ LR） to 5, feminine gender however compare（ - LR）to 0. Conclusion Serum Cys-c may serve as a sensitive indicator for evaluating early stage damage in kidney of diabetes patient.

关 键 词：血清胱抑素C 糖尿病肾病 肾小球滤过率 

分 类 号：R587.2[医药卫生—内分泌]