低血清胆红素与冠心病关系的研究  

Relationship of low serum bilirubin concentration and coronary heart disease

作　　者：陈正贵[1] 顾向明[2] 马立坚[1] 缪灿铭[1] 

机构地区：[1]广州中医药大学中山附属医院心内科,广东省中山市528400 [2]广州中医药大学中山附属医院检验科,广东省中山市528400

出　　处：《中国医药》2006年第2期67-68,共2页China Medicine

摘　　要：目的探讨血清胆红素浓度与冠心病(CHD)的关系。方法检测经选择性冠脉造影确诊的45例冠心病患者及40例冠脉造影正常者空腹血清总胆红素浓度的变化。结果冠心病患者血清总胆红素浓度明显低于冠脉正常者(P<0.01),且冠心病发病年龄越低,胆红素水平也愈低(P<0.05),但冠脉病变支数似与胆红素水平无关(P>0.05)。结论低血清胆红素水平可能是冠心病发病的原因之一,对指导冠心病的诊断和防治具有一定的价值。Objective To explore the change of serum total bilirubin （ STB ） concentration and its clinical significance in patients with coronary heart disease （ CHD ）. Methods Fasting blood STB were measured in 45 patients with CHD and 40 controls with normal coronary arteries ,the changes of STB in patients with CHD were investigated restrospcctively. Results Patients with CHD had a significantly low STB than those of controls （ P 〈 0.01 ）. The earlier age CHD started, the lower lovel of the STB was, but the level of STB didn＇t affect the number of diseased coronary arthery branches （ P 〉 0.05 ）. Conclusion Low STB concentration was probably one of the causes of CHD, and this might be valuble to diagnosis and treatmeat of CHD.

关 键 词：冠心病 胆红素 

分 类 号：R541.4[医药卫生—心血管疾病]