依达拉奉对创伤失血性休克患者氧自由基清除能力的临床研究  

The Clinical Research of Edaravone's Ability of Removing the Oxyradical in the Traumatic Hemorrhagic Shock Patients

作　　者：葛体池[1] 胡永启[1] 余列道[1] 陈纯白[1] 武卫[1] 王和厥[1] 钱定良[1] 

机构地区：[1]温州医学院附属第三医院急诊科,瑞安325200

出　　处：《临床急诊杂志》2006年第3期112-113,共2页Journal of Clinical Emergency

摘　　要：目的探讨依达拉奉对创伤失血性休克患者氧自由基的清除能力。方法将60例患者按创伤严重程度评分(AIS—ISS 法)。并将16分以上的失血性休克患者随机分为依达拉奉治疗组和对照组两组,每个患者治疗前先抽血测定氧自由基和肝功能。对照组用常规方法治疗,治疗组用依达拉奉治疗,然后再测定氧自由基和肝功能,二者作比较。结果治疗组比对照组的氧自由基明显减少,且肝功能有明显改善,均有统计学意义(P<0.05))。结论依达拉奉有较强的清除创伤失血性休克患者氧自由基的功能,能改善患者肝功能,加速失血性休克患者的恢复。Objective In order to research the edaravone＇ s ability in removing the oxyradical in the patients with traumatic hemorrhagic shock. Methods 60 patients of hemorrhagic shock who had more than 16 marks according to the AIS-ISS method were divided into two groups randomly, and every patient was estimated the oxyradical and liver function by blood samples before treatment. The general method was used to treat the patients in the control group, and the edaravone was used to treat the patients in the other group. Finally, the oxyradical and liver function in the two groups were estimated and compared. Results The oxyradical was much less in the treating group than in the control group and the liver function was improved obviously in the treating group, both statistic were different （ P 〈 0. 05 ）. Conclusion the edaravone was the ability of removing oxyradical well in the traumatic hemorragic shock patients, and could improve liver function and helped to recover of the hemorrage shock patients.

关 键 词：创伤失血性休克 依达拉奉 氧自由基 肝功能 

分 类 号：R605.971[医药卫生—急诊医学]