由苯乙腈一步法合成苯乙酸正丁酯  

Synthesis of n-butyl phenylacetate from benzylcyanide by one-step method

作　　者：崔玉民[1] 

机构地区：[1]阜阳师范学院化学系,安徽阜阳236032

出　　处：《化学工程》2006年第6期58-59,76,共3页Chemical Engineering(China)

基　　金：安徽省教育厅自然科学基金资助项目(2004kj303);安徽省"十五"优秀人才--安徽省高校中青年学科带头人培养对象计划经费资助项目(2003YD22)

摘　　要：以苯乙腈和正丁醇为原料,在浓硫酸催化下一步合成苯乙酸正丁酯。由实验确定了优化工艺条件:催化剂用量6.5 g,正丁醇与苯乙腈的摩尔比为2.96∶1,反应温度为120℃,反应时间为6 h,在该优化条件下,产品的产率和纯度分别达到89.8%、99.2%。产品结构经FT-IR1、HNMR确认为苯乙酸正丁酯。n-Butyl phenylacetate was synthesized from benzylcyanide and butanol in the presence of H2SO4 by onestep method. The optimum reaction conditions were determined as follows ： catalyst quantity of 6.5 g the molar ratio of butanol to benzylcyanide of 2.96 ： 1, reaction temperature of 120 ℃, reaction time of 6 h. The yield and the purity of product reached 89.8% and 99.2% respectively. The structure of n-butyl phenylacetate was confirmed by FT-IR, ^1HNMR spectrum.

关 键 词：苯乙腈 正丁醇 苯乙酸正丁酯 一步法 合成 

分 类 号：TQ245.24[化学工程—有机化工]