杯［4］芳烃衍生物的合成和构象研究  

Studies on Synthesis and Conformation of Calix[4] arene Derivatives

作　　者：陆国元[1] 陈中俊[1] 赵荣忠[1] 黄小华[1] 胡宏纹[1] 

机构地区：[1]南京大学化学系,南京师范大学理化测试中心

出　　处：《高等学校化学学报》1996年第8期1244-1246,共3页Chemical Journal of Chinese Universities

基　　金：国家教育委员会科学基金

摘　　要：以对取代酚亚甲基桥三聚体和２，６－二溴甲基对取代酚为原料，在ＴｉＣｌ４催化下环化得到６种新的含不同取代基［Ｃｌ，Ｂｒ，ＣＨ３，Ｃ（ＣＨ３）３］的杯［４］芳烃衍生物，核磁共振谱研究表明：它们在溶液中的优势构象为锥形构象。Six new calix[4]arenes containing different substituents[Cl, Br ,CH3,C(CH3)3] have been prepared from the cyclization of methylene bridged trimers of 4-substituted phenols and 2,6-bis (bromomethyl)-4-substituted phenols over the catalyst of TiCl4 in diglyme solvent with about 25%yield. NMR studies of new calix[4] arenes revealed that methylene protons signals appear at about δ3. 40 and 4. 20 as coupling two double peaks and methylene 13C signals appear at about δ31.5. The preferred conformation of all six calix[4]arenes are cone conformation in solution.

关 键 词：构象 合成 NMR 杯芳烃 

分 类 号：O625.15[理学—有机化学] O641.133[理学—化学]