社区及医院感染中常见细菌的耐药性分析  

Bacterium Drug-resistance Analysis in Community and Nosocomial Infection

作　　者：周仲辉[1] 吴春[1] 王进[1] 邓健康[1] 黄志春 马茂林[3] 任永春[4] 

机构地区：[1]川北医学院附属医院,四川南充637000 [2]仪陇县人民医院感染科 [3]营山县人民医院感染科 [4]南部县人民医院感染科

出　　处：《寄生虫病与感染性疾病》2006年第2期52-55,共4页Parasitoses and Infectious Diseases

摘　　要：目的探讨社区和医院感染中细菌耐药谱的特点。方法药敏试验用KirbyBauer法,根据2003年美国临床实验室标准化委员会(NCCLS)标准判定结果,应用WHONET-5软件对临床分离细菌的药敏结果进行数据分析。结果医院感染480株,常见细菌依次为:铜绿假单胞菌(19.37%),肺炎克雷伯菌(15.83%),大肠埃希菌(11.87%)。社区感染726株,常见细菌为:金黄色葡萄球菌(14.05%),大肠埃希菌(12.67%),凝固酶阴性葡萄球菌(11.43%)。医院感染的金黄色葡萄球菌,凝固酶阴性葡萄球菌,铜绿假单胞菌,大肠埃希菌耐药率明显高于社区感染,差异有统计学意义(P<0.01)。而肺炎克雷伯菌和不动杆菌属差异无统计学意义。结论重视细菌耐药性监测,合理使用抗生素。Objective To explore the characteristic of bacterium drug-resistance spectrum in community and nosocomial infection. Method Drug sensitivity was adopted by Kirby-Bauer method. The criterion for results were referred to National Clinical Committee of Laboratory Standard （NCCLS）. The WHONET-5 software was employed to analyze these bacterium sample data acquired from clinic. Result The common bacteria in nosocomial infection in order were Pseudomonas aeruginosa （19.37%）, Klebsiella pneumoniae （15.83%）, Escherichia coli （11.87%）. At the same time the common bacteria in community infection were Staphylococcus aureus （14.05%）, Escherichia coli （12.67%）, coagulase （-） staphylococcus （11.43%）. The bacterium drug-resistance of Staphylococcus aureus, coagulase （-） staphylococcus, Pseudomonas aeruginosa and Escherichia coli in nosocomial infection was apparently higher than that in community infection （P 〈 0.01）, whereas the infection rate of Klebsiella pneumoniae and Acinetobacter in community and nosocomial infection was no difference. Conclusion Paying attention to bacterium drug-resistance surveillance and rational antibiotic usage is very important.

关 键 词：社区感染 医院感染 细菌 耐药性 

分 类 号：R978.1[医药卫生—药品]