利胆冲剂对胆汁成石趋势的影响  

Effect of cholagogue dry syrup on the lithogenic tendency of bile

作　　者：陈进宏[1] 蔡端[1] 马保金[1] 

机构地区：[1]复旦大学附属华山医院外科,上海200040

出　　处：《肝胆胰外科杂志》2006年第3期142-143,共2页Journal of Hepatopancreatobiliary Surgery

基　　金：国家自然科学基金资助项目(39570695)

摘　　要：目的观察利胆冲剂对胆汁成石趋势的影响。方法60例患者随机分成利胆冲剂组、胆酸钠组和对照组,每组20例。测定服用利胆冲剂前后四项胆汁成石趋势指标:LI,UCB%,BSI和Z值。结果患者服用利胆冲剂前的LI,UCB%,BSI和Z值分别为1.298±0.265,34.72±2.96,0.353±0.093和0.556±0.499;而服用利胆冲剂2周后的LI,UCB%,BSI和Z值分别为0.926±0.208,8.93±1.19,0.154±0.056和0.257±0.211,均显著低于服药前。胆酸钠组和对照组服药前后各项指标无明显差异。结论利胆冲剂能有效降低胆汁的成石趋势。Objective To observe the effect of cholagogue dry syrup on the lithogenic tendency of bile. Methods Sixty patients were randomly divided into cholagogue dry syrup group, sodium cholate group and control group （20 patients in each group）. Four index of lithogenic tendency of bile： LI,UCB%,BSI and Value Z were determined before and after treaunent.Results Before treatment with cholagogue dry syrup , the index of LI , UCB%, BSI and Value Z were 1.298±0. 265 , 34. 72 ±2.96,0.353 ± 0.093 and 0. 556 ± 0.499, respectively, while after treamaem these values were 0. 926 ± 0.208,8.93 ± 1.19,0.154 ± 0.056 and 0.257 ± 0.211, respectively, the latter was all significantly lower than the formet. There were no change in both sodium cholate group and control group. Conclusion Cholagogue dry syrup can decrease the lithogoaaic tendency of bile.

关 键 词：胆结石 利胆冲剂 胆汁 成石趋势 

分 类 号：R285.5[医药卫生—中药学]