系数倍率法测定复方左氟沙星滴耳液中左氧氟沙星和替硝唑含量  

Determination of Levofloxacin and Tinidazole in Compound Levofloxacin Auristilla by K-ratio Method

作　　者：齐菲[1] 侯连兵[1] 

机构地区：[1]南方医科大学南方医院药学部,广东广州510515

出　　处：《中国药业》2006年第6期18-18,共1页China Pharmaceuticals

摘　　要：目的建立复方左氟沙星滴耳液的含量测定方法。方法采用系数倍率法,消除共存组分的干扰。结果被测两组分的吸收度差值与浓度有良好的线性关系,左氧氟沙星和替硝唑的平均回收率分别为99.96%和99.48%;RSD分别为0.9%和1.0%。结论该方法简便、准确,可用于复方左氟沙星滴耳液的质量控制。Objective To establish a method for determination of two components in Compound Levofloxacin Auristilla. Methods The K- ratio method was applied. Results The average recoveries of levofloxacin and tinidazole were 99.96% and 99. 48%, with RSD 0. 9%, 1.0%, respectively. Conclusion The method is simple, accurate, and can be used for quality control of Compound Levofloxacin Auristilla.

关 键 词：系数倍率法 左氧氟沙星 替硝唑 滴耳液 

分 类 号：R927.2[医药卫生—药学] R978.69