血清γ-痕迹蛋白对早期糖尿病肾病的诊断价值  

Evaluation of serum cystatin C as a marker in diagnosis of early diabetic nephropathy.

作　　者：曾娇娥[1] 宁尚侠[1] 王景丽[1] 

机构地区：[1]湖北省荆州市中心医院内分泌科,荆州434020

出　　处：《华中医学杂志》2006年第3期259-260,共2页Central China Medical Journal

摘　　要：目的探讨血清γ-痕迹蛋白(SCysC)在糖尿病肾病早期诊断中的临床价值。方法采用免疫比浊法测定65例糖尿病患者的SCysC浓度,同时测定尿白蛋白排泄率(UAE)、β2-微球蛋白(β2-MG)作为对照。结果UAE升高组(早期糖尿病肾病组)SCysC浓度明显高于UAE正常组(P<0.01),并与UAE及血清β2-MG浓度呈显著正相关。结论SCysC与UAE具有相同的临床意义,可以作为诊断早期糖尿病肾病的一项更简便、快速的敏感指标。Objective To inverstigate the values of serum cystatin C （SCysC） concentration in diagnosis of early diabetic nephropathy. Methods SCysC concentration and urinary albumin excretion（UAE） and β2-MG were measured in 65patients with diabetes mellitus by partical-enhanced turbidimetric immunoassay. Results SCysC was positively correated with UAE or β2-MG Conclusion SCysC is a useful indicator for diagnosis of early diabetic nephropathy and is a more simpler and rapid convenient marker.

关 键 词：糖尿病肾病 Β2-微球蛋白 Γ-痕迹蛋白 尿白蛋白排泄率 

分 类 号：R587.2[医药卫生—内分泌] R735.7[医药卫生—内科学]