超临界二氧化碳萃取苦楝皮中有效成分的初步研究  

Supercritical Carbon Dioxide Extraction of Effective Ingredient in Chinaberry Bark

作　　者：杜爱玲[1] 孙公平[1] 王威强[2] 牟大建[1] 刘宝[1] 

机构地区：[1]山东大学化学与化工学院 [2]山东大学机械工程学院

出　　处：《林产化学与工业》2006年第2期61-64,共4页Chemistry and Industry of Forest Products

摘　　要：采用超临界二氧化碳萃取(SCDE)技术萃取苦楝皮中的有效成分,用均匀设计方法研究超临界萃取的萃取压力、萃取温度、萃取时间和极性提携剂对萃取结果的影响。以L ieberm an反应、Salkwosk i反应、对二甲氨基苯甲醛试液作为苦楝素存在的验证方法,以失重率对总萃取率进行定量表征,510 nm处的吸光度表征萃取物中苦楝素的相对含量,获得了与试验结果一致的模拟方程。在本研究范围内,用SCDE苦楝皮的有效成分时,萃取率可达4.24%,萃取压力为28 MPa。当目的萃取物为苦楝素时,应在35℃下萃取5 h;为获得高的总萃取率,则应高温长时间萃取。不应加入极性强的提携剂。Supercritical CO2 was used to extract the effective ingredient in Chinaberry bark. Lieberman reaction, Salkwoski reaction and dimethylaminobenzaldehyde reaction were used to identify toosendanin. Uniformity design was used for the experiment scheme. Extraction rate （ Y1 ） was measured by means of material weight loss. Absorbency （ Y2 ） at 510 nm was measured to indicate the relative concentration of toosendanin in the extraction. Correlation equations between experimental conditions and Y1 and Y2 have been described respectively. Results showed that optimum extraction conditions of toosendanin are ： pressure 28 MPa, temperature 35 ℃ for Y2, time 5 h and without addition of high-polar modifier .

关 键 词：苦楝树皮 超临界二氧化碳萃取 均匀设计 

分 类 号：TQ91[化学工程] Q949.753.1[生物学—植物学]