鸡骨草治疗ABO母儿血型不合148例的疗效观察  

Observation of therapeutic effect of herba abri in treatmeat of 148 cases with ABO blood group incompatibility in pregnant women and infant.

作　　者：冯惠娟[1] 周秀荣[1] 苏小军[2] 

机构地区：[1]广东省湛江市妇幼保健院妇产科,524038 [2]广东省湛江市妇幼保健院中医科

出　　处：《中国妇幼保健》2006年第12期1712-1714,共3页Maternal and Child Health Care of China

基　　金：广东湛江市2004年度科技攻关项目(编号:19)

摘　　要：目的：观察大剂量鸡骨草治疗孕妇母儿血型不合的临床疗效。方法：将411例母儿血型不合孕妇随机分为3组，A组148例，给予单味鸡骨草治疗；B组140例，给予鸡骨草汤治疗；C组123例，给予西药治疗。每2-4周复查血清免疫性抗体效价。结果：总有效率：A组为92．6％，B组为91．4％，C组为52．9％。产后新生儿ABO溶血病发病率A组为0．8％。B组为7．1％，C组为22．8％。A组与B组比较，无显著性差异（P〉0．05）；A组、B组与C组比较，均有显著性差异（P〈0．01）。结论：大剂量鸡骨草治疗母儿ABO血型不合的疗效与鸡骨草汤相仿，但具有简单、易行、口感好，无毒副作用的优点。对妊娠期用药安全有重要的意义。Objective： To observe the clinical effect of large dosage of herba abri for blood group incompatibility （BGI） in pregnant women Methods： 411 cases of BGI in pregnant women were allocated to three groups randomly. Group A （148 eases） were treated by herba abri alone; group B （140 cases） were treated by herba abri soup; group C （ 123 cases） were treated by western medicine. The titer of seroimmunity antibody was examined every 2-4 weeks. Results： The effective rate was 92.6% in group A, 91.4% in group B and 52.9% in group C. The rate of disease in BGI was 6. 08% in group A, 7. 1% in group B and 22. 8% in group C, having no difference between group A and group B （P 〉 0. 05 ）, having significant difference between group A, group B and group C （ P 〈 0.01） . Conclusion： The curative effect of large dosage of herba abri is similar to conventional prescription, but the former is more simple, convenient and no toxic and tasteful and safe for pregnant period.

关 键 词：妊娠 ABO血型不合 鸡骨草 抗体效价 投药和剂量 

分 类 号：R722.18[医药卫生—儿科]