左旋氨氯地平治疗原发性高血压动态血压观察  

Efficacy of Levamlodipine in Treatment of Hypertension by Ambulatory Blood Pressure Monitoring

作　　者：程江涛[1] 

机构地区：[1]河南中医学院第一附属医院心脏中心,郑州市450000

出　　处：《医药论坛杂志》2006年第10期33-34,共2页Journal of Medical Forum

摘　　要：目的利用动态血压监测技术观察左旋氨氯地平治疗原发性高血压降压疗效。方法选取80例轻中度高血压患者,试验前未服用降压药物或停用其他降压药物1周以上,,给予口服左旋氨氯地平2.5mg/d,连续用药4周,降压疗较差者加量至5mg/d,所有患者于药物治疗前和治疗4周后进行24h动态血压监测。结果左旋氨氯地平能明显降低诊室血压(P<0.05)和24h血压(P<0.05),不良反应发生率低。结论左旋氨氯地平可有效降低轻中度高血压患者诊所血压和24h血压,不良反应少。Objective To observe the efficacy of levamlopine on decreasing 24 - hour blood pressure. Methods 80 patients with mild or moderate essential hypertension were given oral levamlodipine 2. 5mg or 5mg once daily for 4 weeks. 24h ambulatory blood pressure monitoring（ABPM） was performed before therapy and 4 weeks after therapy. Results The clinical blood pressure of all patients were significantly lower after 4 weeks of therapy（ P 〈0. 05）. 24 h SBP and 24 h DBP decreased significantly（ P 〈0. 05）. Conclusion Levamlodipine is an effective angent with less side effects. Levamlodipine can decrease blood pressure during 24 hours.

关 键 词：高血压 左旋氨氯地平 动态血压 

分 类 号：R544.1[医药卫生—心血管疾病]