中药循经敷贴法预防哮喘作用的血清药理学研究  

Serologic Pharmacological Study on Herbal Penetration along Meridians Therapy for Preventing Asthma

作　　者：李袆群 沈惠风[1] 金若敏[2] 李鹤[1] 闵亮[1] 

机构地区：[1]上海交通大学医学院附属仁济医院,上海200127 [2]上海中医药大学,上海201203

出　　处：《中国临床医学》2006年第3期375-376,共2页Chinese Journal of Clinical Medicine

基　　金：上海市科学技术发展基金(024119084)

摘　　要：目的：通过血清药理学研究方法,探讨中药循经敷贴法预防哮喘的作用。方法：把造模豚鼠随机分为对照组、中药治疗组、氨茶碱敷贴组、氨茶碱注射组,分别敷贴生理盐水、中药、氨茶碱,以及腹腔注射氨茶碱。用药7d后取血清,观察用血清处理后的豚鼠离体气管条受氯化乙酰胆碱(Ach)诱发的收缩情况。以收缩百分比为疗效评判指标。结果：治疗组与模型组有显著性差异。结论：中药循经敷贴法具有预防哮喘作用。Objective：Serologic pharmacological test was used to study the effect of herbal penetration along meridians therapy to prevent asthma. Methods：Asthmatic model guinea pigs were divided into 4 groups randomly, model control group, herbal treatment group, ainophyline application group and ainophyline injection group, which applied by 0. 9~ NaCI, herbal powder, ainophyline respectively. Ainophyline injection group was injected by abdomen. Got serum after 7 days. The effect of the serum to resist tracheal spiral strips constriction induced by Ach were observed. Score up the constriction rate as target. Results：The rates of treatment group were higher significantly than that of control group. Conclusion： Herbal penetration along meridians therapy has the effect of preventing asthma.

关 键 词：哮喘 中药敷贴 气管条 氯化乙酰胆碱 

分 类 号：R256.12[医药卫生—中医内科学]