影响回路内麻醉气体吸附器效果多因素分析  

Charcoal and Isoflurane Alveolar Washout in Low-flow Circuit

作　　者：李华 朱彪[2] 孙慧娟 高勇梁 

机构地区：[1]上海市大华医院麻醉科,上海200237 [2]复旦大学附属中山医院麻醉科,上海200032

出　　处：《中国临床医学》2006年第3期489-490,共2页Chinese Journal of Clinical Medicine

摘　　要：目的：研究XF—9801型活性炭吸附器对异氟醚吸入麻醉的吸附效果的影响因素。方法：20例择期手术病人,术中根据手术需要调整蒸发器刻度维持异氟醚呼气末浓度0.6～1.0MAC,记录病人的麻醉持续时间和呼气末异氟醚浓度,手术结束,使用回路内吸附器后,达到呼气末异氟醚浓度0.2%和0.3%所持续的时间,将该时间与麻醉持续时间、呼气末异氟醚浓度、体重、年龄进行逐步回归分析。结果：回路内吸附器使用后,达到呼气末异氟醚浓度0.2%和0.3%所持续的时间分别为8.0±2.3min和2.5±1.2min,而且该时间与呼气末异氟醚浓度、体重、麻醉持续时间和年龄呈现明显的相关性(P＜0.05)。病人的苏醒时间为12.3±4.5min。结论：回路内吸附器使用后,呼气末异氟醚浓度0.2%和0.3%所持续的时间分别与呼气末异氟醚浓度、体重、麻醉持续时间和年龄呈现明显的相关性。使用回路内活性炭吸附器后病人的苏醒时间明显缩短。Objective：The inclusion of charcoal filters in anaesthetic low-flow systerms contributes to the acceleration of the kinetics of isoflurane,the study was to analyse the factors affect elimination of isofiurane. Methods： In twenty paxienls scheduled for various surgery, ventilated with a low-flow system （Drage-Vapor 2000 with rebreathing cassette） with a mean total flow of 1L/rain. The anesthesia time and the expiratory concentration of isoflurane were recorded. Similarly, the time of 0. 2% and 0. 3% of the expiratory concentration of isoflurane after using charcoal filters. Results：Awaken was complete within 5 minutes from stopping isoflurane and including charcoal in the circuit. The time of 0. 2% and 0. 3% of the expiratory concentration of isoflurane after using charcoal filters were 8.0± 2. 3min and 2. 5 ± 1.2min,respectivecly and these time were positively related with the anesthesia time and the expiratory concentration of stopping isoflurane anaesthesia. Similarly with the weight of patients. Conclusion：The anaesthetic level is more easily controllable and volatile anaesthetics can be immediately removed from delivery system. The time of 0. 2% and 0.3% of the expiratory concentration of isoflurane after using charcoal filters were positively related with the anesthesia time and the expiratory concentration of stopping anesthesia.

关 键 词：异氟醚 活性炭吸附器 多元线性回归 吸入麻醉 

分 类 号：R645.2[医药卫生—外科学]