稳心颗粒与乙胺碘肤酮联用治疗慢性房颤的临床研究  

Treatment Effect of Wenxin Grain Combined with Amiodarone for Chronic Atrial Fibrillation

作　　者：朱永彪 张丽 董喜敏 

机构地区：[1]河南省地质医院急诊科,河南郑州450006

出　　处：《河南职工医学院学报》2006年第3期190-192,共3页Journal of Henan Medical College For Staff and Workers

摘　　要：目的探讨稳心颗粒与乙胺碘肤酮联用治疗慢性房颤的临床疗效。方法将168例慢性房颤病人随机分为稳心颗粒加乙胺碘肤酮组(A组)57例、乙胺碘肤酮组(B组)55例、稳心颗粒组(C组)56例,观察治疗前后临床症状和心律失常改善情况及不良反应。结果治疗前后动态心电图观察对比:A组总有效率为91.22%(52例),B组总有效率为69.09%(38例),C组总有效率为69.64%(39例)。A组与B组比较P<0.05差异有显著性,与C组比较P<0.05,差异有显著性,B组与C组比较P>0.05,差异无显著性;治疗后临床症状改善情况:A组与B组比较P<0.05,差异有显著性,与C组比较P<0.05,差异有显著性,B级与C组比较P>0.05,差异无显著性。结论稳心颗粒与乙胺碘肤酮联用治疗慢性房颤明显优于各自单用疗效,且不良反应少。Objective To explore the clinical effect of Wenxin Grain combined with Amiodarone in the treatment of chronic atrial fibrillation. Methods 168 patients with atrial fibrillation were divided into three groups. Group A was treated with Wenxin Grain and Amiodarone; group B with Amiodarone; group C with Wenxin Grain. Then the improvement of clinical symptoms and Holter and the rat of adverse effects were observed. Results After treatment, Holter compared with the state before treatment, the total effective rate of group A was 91.22 percent, the total effective rate of group B was 69.09 percent, the total effective rate ofgroup C was 69.64 percent. Comparing group A with group B and C, there was significant statistical difference（ P 〈 0.05）. Comparing group B with group C,there was no statistical difference（ P 〈 0.05）. After treatment,the clinical symptom improvement of group A was significantly better than that of group B and C（ P 〈 0.05）.The rate of the adverse effects of group A and C was lower than that of group B. Conclusion Wenxin Graincombined with Amiodarone is more effective and safe than the two alone in treating patients with chronic atrialfibrillation.

关 键 词：稳心颗粒 乙胺碘肤酮 慢性房颤 动态心电图 

分 类 号：R541.75[医药卫生—心血管疾病]