累及眼部的白塞病患者血浆瘦素含量  

Evaluation of serum leptin concentration in Behcet’s disease with ocular involvement

作　　者：Kavuncu S. KoF. Kurt M. 陈立军 

机构地区：[1]MSB Lojmanlari 13/31, Oran■ehri, Ankara, Turkey

出　　处：《世界核心医学期刊文摘（眼科学分册）》2006年第5期38-38,共1页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：PURPOSE: To assess the correlation between the serum leptin concentration and ocular involvement in patients with Behcet’s disease. Methods: The study included 28 male consecutive patients with Behcet’s disease (group A, aged 19-59, median 35.5 years) and 15 male healthy control subjects (group B, aged 25-45, median 35 years). The body mass index (BMI) was calculated for each subject at the study enrollment stage. We measured serum leptin, neutrophil count and erythrocyte sedimentation rate (ESR). Kruskal-Wallis variance analysis and the Mann-Whitney U-test were used for statistical analysis. Results: The age and BMI between the patients with ocular Behcet’s disease and the control group were not different. White cell count and ESR values were found to be significantly higher among patients with Behcet’s disease and ocular involvement (p< 0.001). The median serum leptin concentrations were as follows: group A: 2.66 (0.57-7.02 ng/ml) and in group B: 2.55 (1.55-7.82 ng/ml). There was no statistically significant difference between the groups. Conclusion: Serum leptin level does not correlate with ocular involvement in patients with Behcet’s disease.Purpose： To assess the correlation between the serum leptin concentration and ocular involvement in patients with Behcet＇ s disease. Methods： The study included 28 male consecutive patients with Behcet＇ s disease （group A, aged 19 -59, median 35.5 years） and 15 male healthy control subjects （group B, aged 25-45, median 35 years） . The body mass index （BMI） was calculated for each subject at the study enrollment stage. We measured serum leptin, neutrophil count and erythrocyte sedimentation rate （ESR）. Kruskal-Wallis variance analysis and the Mann-Whitney U-test were used for statistical analysis. Results： The age and BMI between the patients with ocular Behcet＇ s disease and the control group were not different.

关 键 词：患者血浆 眼部受累 瘦素含量 白塞病 BEHCET病 红细胞沉降率 平均浓度 白细胞数 正常对照组 男性患者 

分 类 号：R541.6[医药卫生—心血管疾病] R771.3[医药卫生—内科学]