重症孪生胎儿间输血综合征宫内激光凝固治疗后的长期心脏随访  

Long term cardiac follow up of severe twin to twin transfusion syndrome after intrauterine laser coagulation

作　　者：Herberg U Gross W Bartmann P. 田志 

机构地区：[1]Division of Paediatric Cardiology,Children’ s Hospital, University of Bonn,Adenauerallee 119, 53113 Bonn,Germany,Dr.

出　　处：《世界核心医学期刊文摘（心脏病学分册）》2006年第5期35-36,共2页

摘　　要：Objective: To assess long term changes in cardiac morphology and function in survivors of severe twin to twin transfusion syndrome(TTTS) after intrauterine laser coagulation of placental anastomoses. Design: Prospective follow up of fetuses with severe TTTS treated by laser coagulation of intrauterine placental anastomoses. Fetal echocardiography and Doppler studies of feto-placental haemodynamic function were performed at the time of laser coagulation(median gestational age of 21.7 weeks). Postnatal cardiac follow up included a detailed echocardiographic study of systolic and diastolic cardiac function at a median age of 21.1 months. Setting: PaediatricObjective： To assess long term changes in cardiac morphology and function in survivors of severe twin to twin transfusion syndrome（TTTS） after intrauterine laser coagulation of placental anastomoses. Design： Prospective follow up of fetuses with severe TITS treated by laser coagulation of intrauterine placental anastomoses. Fetal echocardiography and Doppler studies of feto-placental haemodynamic function were performed at the time of laser coagulation（median gestational age of 21.7 weeks）. Postnatal cardiac follow up included a detailed echocardiographic study of systolic and diastolic cardiac function at a median age of 21.1 months. Setting： Paediatric cardiology unit. Patients： 89 survivors from 73 consecutive pregnancies with severe TTTS. Results： Before laser treatment, 28 of 51 （54. 9% ） recipient twins had typical signs of cardiac dysfunction clue to volume overload and 9 of 38（23.7% ） donors had absent or reversed end diastolic flow in the umbilical artery.

关 键 词：激光凝固治疗 孪生胎儿 输血综合征 心脏形态 治疗后 随访 宫内 重症 超声心动图检查 胎儿超声心动图 

分 类 号：R697.320.5[医药卫生—泌尿科学] R339.146[医药卫生—外科学]