血浆黏度、纤维蛋白原和D-二聚体在脑血栓检测中的意义  被引量:2

The Significance of Plasma Viscosity,Fibrinogen and D-dimer Concentration in Detecting Cerebral Thrombus

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作  者:黄美群[1] 刘惠兰[1] 王发雄[1] 

机构地区:[1]广东省人民医院检验科,广州510080

出  处:《血栓与止血学》2006年第3期116-117,119,共3页Chinese Journal of Thrombosis and Hemostasis

摘  要:目的通过观察脑血栓患者血浆黏度(PV)、纤维蛋白原(Fbg)和D二聚体(D-D)水平的变化,分析其对早期脑血栓的检测意义。方法收集60例脑血栓患者和50例健康体检者的血液,分别检测两组标本在不同时间内的血浆黏度、纤维蛋白原和D-D含量;然后比较两组标本的检测结果。结果在24h内,早期脑血栓组的PV、Fbg结果高于对照组,其差异具有统计学意义(P<0.05);而两组D-D检测结果的差异不大;至第5d,脑血栓组Fbg水平与24h内的检测结果相比无明显变化,而血浆黏度仍然持续上升,D-D水平也开始上升;第8d后,PV、Fbg和D-D水平均明显高于健康对照组,其差异具有统计学意义(P<0.001)。结论监测早期脑血栓患者的PV、Fbg和D-D水平,对指导临床医生早期进行抗血栓治疗非常必要。Objective To investigate the significance of plasma viscosity, fibrinogen(Fbg) and D-dimer(D-D) concentration in detecting acute cerebral thrombus through analyzing their changes in patients with cerebral thrombus. Methods Collecting the blood samples of 60 patients with cerebral thrombus and 50 normal persons, testing and comparing the plasma viscosity, the concentration of Fbg and D-D. Results There are significant difference levels in PV and Fbg in patients with acute cerebral thrombus in comparison with the normal controls in 24 hours (P 〈 0.05), but there is no obvious difference between the detecting results in D- D of the two groups. There is no evident change in Fbg after 5 days in patiens, but PV increases continuously, D-D starts upgrade, too. There are significant increase (P 〈 0.01 ) in PV, Fbg and D-D concentration in comparison with the controls after 8 days. Conclusion It' s necessary for guiding doctors to carry out antithromb treatment to test plasma viscosity, the concentration of Fbg and D-D in patients with acute cerebral thrombus.

关 键 词:早期脑血栓 血浆黏度 纤维蛋白原 D-二聚体 

分 类 号:R692.5[医药卫生—泌尿科学]

 

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