肾病综合征、尿毒症患者血清生长激素水平检测及其意义  

Detection of Serum Levels of Growth Hormone and Its Clinical Significance in Patients with Nephrotic Syndrome and Uremia

作　　者：谭丽玲[1] 贾龙梅[1] 习卫民[1] 汪健[1] 房向东[2] 

机构地区：[1]南昌大学第二附属医院核医学科,江西南昌330006 [2]南昌大学第二附属医院肾内科,江西南昌330006

出　　处：《江西医学院学报》2006年第3期100-101,共2页Acta Academiae Medicinae Jiangxi

摘　　要：目的观察肾病综合征、尿毒症患者血清生长激素(GH)水平。方法采用放射免疫分析法测定30例肾病综合征患者、50例尿毒症患者、30例健康对照组血清GH浓度。结果肾病综合征患者血清GH浓度(2.63±1.00)ng/mL明显低于健康对照组(5.48±0.96)ng/mL(P<0.05);尿毒症患者血清GH浓度(17.92±5.81)ng/mL明显高于健康对照组(P<0.05)。结论肾病综合征患者血清GH浓度明显降低;尿毒症患者虽然GH水平明显升高,但机体对其产生抵抗,故其GH水平存在相对不足。Objective To observe the levels of growth hormone（GH） in patients with nephrotic syndrome and uremia. Methods With the radio immunoassay,the concentration of GH in serum of 30 patients with nephrotic syndrome, 50 patients with uremia and 30 normal persons as the control were detected. Results The concentration of GH in serum of the patients with nephrotic syndrome was 2. 63 ± 1.00ng/mL and obviously lower than that of the control group （5. 48 ± 0. 96）ng/mL（P〈0. 05） ;and the concentration of GH in serum of the patients with uremia was 17. 92±5.81ng/mL and obviously higher than that of the control group（P〈0.05）. Conclusion The levels GH levels of patients with nephrotic syndrome decreased obviously;and the GH levels of patients with uremia may appear relative shortage, because the body can produce resistent to growth although the levels of GH have risen remarkably.

关 键 词：生长激素 肾病综合征 尿毒症 

分 类 号：R692[医药卫生—泌尿科学] R446.119[医药卫生—外科学]