拜安捷^(TM)血糖监测仪测定末梢毛细血管血糖与全自动生化分析仪测定静脉血浆血糖的临床对比研究  

Comparison of periphery capillary whole blood glucose using BREEZE^(TM)blood glucose meter and venous plasma glucose using laboratory autoanalyzer

作　　者：姚军[1] 高妍[1] 纪立农[2] 郭晓蕙[1] 陈澜[1] 王波澜[2] 

机构地区：[1]北京大学第一医院内分泌科,100034 [2]北京大学人民医院内分泌科

出　　处：《中华内分泌代谢杂志》2006年第3期i0009-i0012,共4页Chinese Journal of Endocrinology and Metabolism

摘　　要：目的评价拜安捷^(TM)血糖监测仪的精确性及其测定毛细血管血糖(capillary blood glucose,CBG)与全自动生化分析仪测定静脉血浆血糖(venous plasma glucose,VPG)的相关性。方法188例糖尿病或非糖尿病受试者在空腹及标准餐后30、60、120 min测定VPG同时用拜安捷^(TM)血糖监测仪测定CBG。用10台拜安捷^(TM)血糖监测仪分别用三个批号的试纸对低、中、高浓度水平的核对液进行测定计算其批内差异和批间差异。结果在空腹及进标准餐后不同时间点,CBG与VPG均有良好的相关性,r均在0.950以上。误差分析图显示98.94%的数据落在A区。在不同血糖浓度下,CBG与VPG的相对差值均在5%以下。在低浓度、正常浓度及高浓度范围内,采用不同批号试纸检测,批内差异和批间差异CV值均＜5%。结论拜安捷^(TM)血糖监测仪的准确性和精确性高,在空腹和进餐后不同时间及不同血糖浓度下均能较准确地反映血糖的真实水平。Objective To evaluate the precision of BREEZETM glucose monitor and correlation of glucose measurements between fingertip capillary whole blood glucose （CBG） using BREEZETM glucose monitor and venous plasma glucose （VPG） using autoanalyzer. Methods All samples of venous plasma and fingertip blood from 188 diabetes or non-diabetes patients were detected for glucose level at fasting, 30, 60 and 120 min postprandial. BREEZETM glucose monitor and autoanalyzer measured CBG and VPG respectively. Intra- and inter-coefficients of variations were determined using 10 BREEZE^TM glucose monitors with normal, slight high and high glucose levels for the three lots of strips. Results The correlation coefficients between CBG and VPG were all higher than 0. 950 at fasting and different postprandial time. 98.94% of all measurements were in the A zone when using error-grid analysis. The relevant differences between CBG and VPG were less than 5% at different blood glucose concentrations. The intra- and inter-coefficients of variations of blood glucose values at different blood glucose concentrations using different lots of strips were within 5%. Conclusion BREEZETM glucose monitor provides high accurate and precise glucose readings on fasting and different postprandial time points over a variety of blood glucose concentrations.

关 键 词：糖尿病 血糖仪 毛细血管血糖 静脉血浆血糖 

分 类 号：R587.1[医药卫生—内分泌] R446.1[医药卫生—内科学]