帕金森病患者的交感神经皮肤电反应的初步探讨  

A Primary Study of Sympathetic Skin Response in Parkinson's Disease Patients

作　　者：黄慧[1] 王晓明[1] 赵小琼[1] 胡建秀[1] 马英[1] 

机构地区：[1]川北医学院附院神经内科,四川南充637000

出　　处：《川北医学院学报》2006年第3期229-230,共2页Journal of North Sichuan Medical College

基　　金：四川省医学重点学科建设项目(2002川卫138号)

摘　　要：目的探讨交感神经皮肤电反应(SSR)在判断帕金森病(PD)患者自主神经功能障碍中的价值。方法采用肌电/诱发电位仪对PD患者和健康人分别进行SSR检测并对比分析。结果PD患者SSR潜伏期上肢为(1.89±0.40)s,下肢为(2.19±0.56)s;波幅上肢为(0.68±0.50)mV,下肢为(0.49±0.58)mV,分别较对照组(1.48±0.12)s、(1.93±0.19)s、(2.09±0.20)mV、(1.25±0.38)mV明显延长及降低,两组比较有显著性差异(p值均<0.05)。结论SSR对判断PD患者的自主神经功能障碍具有一定临床意义。Objective To study the value of sympathetic skin response in assessing the autonomic nerve disorder in PD patients. Methods Using electromyography/evoked potential equipment, sympathetic skin response of PD patients and healthy people were detected and the data were compared. Results The mean latent period of upper limbs in PD patients was （1.89 ± 0.40）s, and the lower（2.19 ± 0.56）s , obviously longer than that of the control group which were （1.48 ± 0.12）s and （1.93 ± 0.19 ）s respectively; the mean amplitude in upper limbs was （0.68 ± 0.50）mV, and the lower （0.49 ± 0.58）mV, obviously decreased than that of the control group which were （2.09 ± 0.20）mV and （1.25 ± 0.38 ）mV respectively. Significance was found between the PD patients and the control group（p 〈 0.05）. Conclusion Clinical value of sympathetic skin response was found in assessing the autonomic nerve disorder in PD patients.

关 键 词：帕金森病 交感神经皮肤电反应 自主神经功能障碍 

分 类 号：R322.99[医药卫生—人体解剖和组织胚胎学]