血钠水平预测小儿单纯热性惊厥再发的实用价值  

The Practicality Values of Serum Sodium Levels that Predict Simple Febrile Convulsion Recurrence

作　　者：叶环[1] 赵再召[2] 徐美春[2] 华珍春[1] 刘慧芳[1] 王霞[2] 

机构地区：[1]杭州师范学院医学院附属医院儿科,杭州310015 [2]浙江大学医学院附属儿童医院急诊科

出　　处：《中国预防医学杂志》2006年第3期174-176,共3页Chinese Preventive Medicine

摘　　要：目的 探讨单纯性热性惊厥及惊厥再发与血钠浓度的关系；支持或否决血钠生化分析在热性惊厥及惊厥再发的临床价值。方法 从2004年2月到2005年8月观察、分析了160例年龄在6月龄～5岁急诊惊厥患儿的血钠水平，其中单次抽搐的单纯性热性惊厥130例，多次抽搐（再发）的单纯性热性惊厥30例，所有患儿均在静脉输液前抽出外周静脉血送血钠生化分析。结果 再发单纯性热性惊厥组比单发单纯性热性惊厥组血钠平均值低，两组间血钠值的比较，统计显示：t=3．6167，P＜0．01，差异有统计学意义。结论 支持国内外大多数学者的观点，即低血钠可能是同一次热性疾病中、24h内惊厥再发的诱因之一，临床上血钠浓度检测应作为热性惊厥病人的常规检查项目。Objective To study the relationship between lower sertum sodium levels and an increase risk of developing recurrent convulsion in the same febrile illness in children with simple febrile convulsion. Methods Serum sodium chemistry analysis was performed in 160 children with 6 months to 5 years of age who presented to the Emergency rooms of fire Affiliated children＇ Hospital of Medical College of Zhejiang University and Affiliated Hospital of Medical College of Hangzhou Teachers College from February 2004 to August 2005.The cases were separated into two groups.One group belonged to simple febrile convulsion of 1 seizure in 24 hours （ n = 130） ; Another group was recurrent ＂simple＂ febrile convulsion with more than 1 seizures in 24 hours （ n = 30） . Results The mean serana sodium value of the recurrent ＂simple＂ febrile convulsion group was significantly lower than the moan sodium value for children with 1 seizure simple febrile convulsion group （ P 〈 0.01 ） . Conclusion We concluded that hyponatremia may increase the risk for multiple seizures within 24 hours during the same febrile illness.Serum sodium levels may prediete seizure recurrence.

关 键 词：单纯性 热性惊厥 血钠浓度 再发 

分 类 号：R720.597[医药卫生—急诊医学] R743.3[医药卫生—儿科]