高血压患者血压昼夜节律消失与血液流变学的变化  

Relationship of diurnal rhythm of blood pressure and hemorrheology in patients with hypertension

作　　者：覃天锦[1] 李秀琴[1] 丁乃勇[1] 

机构地区：[1]济南市第三人民医院,山东省济南市250101

出　　处：《中国心血管病研究》2006年第7期530-531,共2页Chinese Journal of Cardiovascular Research

摘　　要：目的观察高血压昼夜节律消失与血液流变学之间的关系。方法选择行24h动态血压检测的Ⅰ～Ⅱ级原发性高血压患者148例,男性83例,女性65例。根据夜间平均动脉压下降10%以上或以下的标准,将原发性高血压患者分为杓型患者组(85例)和非杓型组(63例)。空腹采静脉血,测定血液流变血各项指标。结果非杓型组的凝血因子Ⅰ(Fg)、红细胞压积(Hct)、全血黏滞度(ηb)、血浆黏滞度(ηp)、全血低切黏度(ηbI)、红细胞聚集指数(EAI)显著高于杓型组(P<0.01,P<0.05)。结论高血压昼夜节律消失与血液流变学异常呈正相关。Objective To investigate the relationship between loss of diurnal rhythm of blood pressure and hemorrheology in essential hypertention （EH）. Methods According to ambulatory blood pressure, 148 patients （83 male, 65 female） with EH （stage Ⅰ and Ⅱ ） were divide into two groups, dipper （n=85） and non dipper （n=63）. Hemorrheologic indexes were measured. ResuIt The fihrinogen （Fg）, Hct,ηh, ηP,ηhI,erythrocyte agglutination index （EAI）were significantly higher in non dipper group than that in dipper group （P〈0.05,P〈0.01）. Conclusion The loss of diurnal rhythm is closely correlated with abnormal hemorrheology in EH.

关 键 词：高血压 昼夜节律 血液流变学 

分 类 号：R544.1[医药卫生—心血管疾病]