老年高血压与胰岛素抵抗相关因素分析  

Analysis of Relative Factors of Insulin Resistance and Senile Hypertension

作　　者：祖木拉提.哈斯木 邱洪敏[2] 刘华[2] 

机构地区：[1]新疆乌鲁木齐市第一人民医院分院,乌鲁木齐830011 [2]新疆医科大学第一附属医院,乌鲁木齐830054

出　　处：《地方病通报》2006年第3期24-26,共3页Endemic Diseases Bulletin

摘　　要：目的原发性高血压目前被认为是胰岛素抵抗综合征的一部分,我们对老年高血压患者中有关因素进行分析讨论。方法高血压组68人,平均年龄65.7岁,对照组53例,平均年龄63.9岁。测空腹血糖(FBG)、胰岛素(FINS)、血脂4项甘油三酯(TG)。计算体重指数BM I=体重(kg)/身高(m)2、脂肪分布指数WHR=腰围/臀围、胰岛素敏感指数ISI=I/FBG×FINS。结果高血压组的BM I,WHR,FBG,FINS,TG水平高于对照组,ISI低于对照组。经多元分析,ISI与TG,BM I,WHR呈负相关,与HDL呈正相关。结论老年高血压组存在有胰岛素抵抗,这是造成高血压病并发冠心病发生的重要原因之一。Objective To analyze and discuss the relative factors of insulin resistance and senile hypertension. Methods There were 68 cases with hypertension of 65.7 average age and 53 cases of the control with the mean age of 63.9. Fasting blood glucose （ FBG ）, fasting insulin （ FINS ）, lipids such as triglyceride were detected and body mass index [ BMI = body weight （ kg ）/body height （ m ）^2 ], lipid distribution index （ WHR = waistline/hip circumference）, insulin sensitivity index （ ISI = I/FBG × FINS） were measured. Resuits The levels of BMI, WHR, FBG, FINS, TG in hypertension group were higher than those in the control while ISI in the hypertension was lower than that in the control. By multiple analysis, there was negative correlation between ISI and TG, BMI, WHR, and positive correlation between ISI and HDL. Conclusions There is insulin resistance in senile hypertension. It is one of the important reasons for hypertension combined with coronary heart disease.

关 键 词：老年高血压 胰岛素抵抗 

分 类 号：R544.1[医药卫生—心血管疾病]