中药协定方治疗阴虚血淤型2型糖尿病的临床研究  

Clinical observations of traditional Chinese medicine prescription in treatment of type 2 diabetes of yin deficiency and blood stasis

作　　者：郑敏[1] 杨宏杰[1] 李昀昊[1] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院内分泌科,200437

出　　处：《上海医学》2006年第6期369-371,共3页Shanghai Medical Journal

摘　　要：目的研究以滋阴补肾、活血化淤为治疗原则的中药协定方对阴虚血淤型2型糖尿病患者糖、脂代谢及血液流变学的干预作用。方法将60例阴虚血淤型2型糖尿病患者随机均分为治疗组(予中药协定方)和对照组(予糖脉康颗粒冲剂),观察治疗前和治疗8周后中医证候及血糖、血液流变学、血脂等指标,同时观察药物的不良反应。结果治疗8周后,治疗组中医单项证候、中医证候总积分、空腹及餐后2h血糖、血液流变学显著改善,且与对照组的差异有显著性(P＜0．05)；治疗组治疗后三酰甘油明显改善,而对照组无明显变化。两组均未见不良反应。结论中药协定方治疗阴虚血淤型2型糖尿病患者8周后中医证候及血糖、血液流变学、血脂指标均显著改善,提示该协定方有改善糖、脂代谢及血液流变学的作用,安全性良好。Objective To observe the clinical efficacy of traditional Chinese medicine prescription in the treatment of type 2 diabetes of yin deficiency and blood stasis involving metabolism of glucose and lipid together with intervening of blood circulation. Methods 60 subjects were randomized into two groups： treatment group, 30 cases undergone traditional Chinese medicine prescription and control group, 30 cases with ＂Zhonghuitang Maikang＇. Both groups were undertaken a course of two months. The parameters as clinical symptoms, blood glucose, blood lipid and hemorheology before and after the trial and abverse effects were observed. Results Good effects were obtained in both groups, but the clinical symptoms and blood glucose improved more significantly in the treatment group than those in the control group（P〈0.05）. No adverse effects occurred in both groups. Conclusion Type 2 diabetes of yin deficiency and blood stasis patients show significant improvement in clinical symptoms, blood glucose, blood lipid and hemorheology after traditional Chinese medicine prescription therapy with well tolerance and no adverse effects.

关 键 词：2型糖尿病 中药协定方 阴虚血淤型 

分 类 号：R259[医药卫生—中西医结合]