羧甲基纤维素预防术后粘连的研究进展  

RESEARCH ADVANCE IN PREVENTION OF POSTOPERATIVE ADHESION USING CARBOXYMETHYL-CELLULOSE

作　　者：肖海军[1] 侯春林[1] 顾其胜 刘亚平[1] 

机构地区：[1]第二军医大学长征医院骨科,上海200003 [2]上海其胜生物材料技术研究所

出　　处：《中国修复重建外科杂志》2006年第7期762-765,共4页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：目的了解羧甲基纤维素(carboxymethylcellulose,CMC)预防术后粘连研究的进展。方法广泛查阅近年来的相关文献,对CMC的理化特性、预防粘连的机制、吻合口愈合的影响以及在动物实验/临床上的应用效果进行综述。结果CMC是一种组织相容性良好、可生物降解及理化特性稳定,能有效预防术后粘连的多糖类化合物。结论CMC用于预防术后粘连具有较为广阔的前景。Objective To study the prevention of postoperative adhesion using carboxymethylcellulose（CMC）. Methods The literature was reviewed extensively, concerning the physical and chemical characters of CMC, the mechanism of preventing adhesion, the effect on healing of anastomoses, the experimental researches and the clinical application. Results CMC was a polysaccharide with favorable biocompatibility, biodegradation, stable physical and chemical characters, and it can prevent postoperative adhesion. Conclusion CMC is with a wide outlook in prevention of postoperative adhesion.

关 键 词：羧甲基纤维素 术后 粘连 预防 

分 类 号：R619[医药卫生—外科学]