医用SiO_2气凝胶/壳聚糖复合材料的制备  

Preparation of SiO_2 aerogel/chitosan composite material for biomedical applications

作　　者：曾淼[1] 刘敬肖[1] 史非[1] 王继红[1] 郭爽[1] 

机构地区：[1]大连轻工业学院化工与材料学院,辽宁大连116034

出　　处：《大连轻工业学院学报》2006年第2期121-124,共4页Journal of Dalian Institute of Light Industry

基　　金：辽宁省博士启动基金资助项目(20021054);辽宁省教育厅资助项目(2020701096)

摘　　要：用环境干燥法,通过静电作用制备了SiO2气凝胶/壳聚糖复合材料。SiO2气凝胶为基体,乙醇水溶液为分散介质,三聚磷酸钠为强电解质。采用扫描电镜、红外光谱仪分析其形貌和组成,并实验研究了此复合材料对药物庆大霉素(Gen)的担载能力。结果表明,这种SiO2气凝胶/壳聚糖复合材料对药物包覆率为17.32%。The SiO2 aerogel/chitosan composite materials were prepared by ambient drying method under electrostatic effect. SiO2 aerogel used as the base, ethanol/water as the separating medium, and STPP（sodium tripolyphosphate）as the strong electrolyte. The surface morphology and composition of this composite material were investigated by scanning electronic microscope（SEM）and Fourier transform infrared spectrophotometer（FTIR）, Its drug（gentamicin）loading performance was studied. It reveals that the drug encapsulation efficiency of this kind of composite material approaches 17.32%.

关 键 词：SIO2气凝胶 壳聚糖 复合 静电作用 庆大霉素 

分 类 号：TB332[一般工业技术—材料科学与工程]