成都地区乙肝患者重叠感染其它型肝炎病毒的分析  

Analysis of coinfection of other hepatitis virus in 196 hepatitis B patients in Chengdu city

作　　者：熊杰[1] 范志能 白生华[2] 古宇[1] 

机构地区：[1]成都军区总医院检验科,四川成都610083 [2]成都医学院第一附属医院,四川成都610500

出　　处：《西部医学》2006年第4期513-514,共2页Medical Journal of West China

摘　　要：目的探讨乙型肝炎患者重叠感染其它型肝炎病毒的情况。方法采用酶联免疫吸附法对成都地区196例乙型肝炎患者血清进行HAV IgM、HCV IgM、HDV IgM、HEV IgM、HEV IgG和HGV IgM的检测。结果196例乙型肝炎患者中重叠感染其它型肝炎病毒的共有18例(9.18%),其中HBV-HCV 2例,HBV-HDV 1例,HBV-HEV 12例,HBV-HGV 1例,本次调查未发现HBV-HAV重叠感染。不同乙肝两对半模式重叠感染率差异无统计学意义(精确概率法,P=0.118)。结论乙肝患者重叠感染其它型肝炎具有地区特异性,对于乙肝患者同时注意检查有无其他型肝炎病毒的重叠感染,对估计病情和治疗具有重要意义。Objective To investigate the coinfection of other hepatitis virus in hepatitis B patients in Chengdu city. Methods HBV markers, anti-HAV IgM, anti-HCV IgM, anti-HDV IgM, anti-HEV IgM/IgG and anti-HGV IgM of serum samples collected from 196 hepatitis B patients were detected by ELISA. Results Out of 196 serum samples, 18 showed coinfection （9.18%）, in which, there were 2 HBV-HCV（1.02%）, 1 HBV-HDV（0.51%）, 12 HBV-HEV（6. 12%）, 1 HBV-HGV（0.51%）and 1 HBV-HEV-HGV（0.51%） coinfection. No HBV-HAV coinfection was detected in this series. In different HBV-M patterns, there was no statistic difference of the ratio of coinfection （X^2= 1.72, P〉0. 05）. Conclusion The coinfection of hepatitis virus shows area characteristic. It is important to detect other hepatitis virus at the time to detect HBV.

关 键 词：乙型肝炎病毒 重叠感染 酶联免疫吸附法 

分 类 号：R512.62[医药卫生—内科学]