REV和ALV-J共感染鸡病毒血症及抗体反应的相互影响  

Interaction of Virema and Antibody in Chickens Coinfected with REV and ALV-J

作　　者：孟珊珊[1] 崔治中[1] 孙淑红[1] 

机构地区：[1]山东农业大学动物科技学院,山东泰安271018

出　　处：《中国兽医学报》2006年第4期363-366,共4页Chinese Journal of Veterinary Science

基　　金：国家自然科学基金重点资助项目(30330450)

摘　　要：为了研究禽网状内皮增生病病毒(REV)、禽J亚群白血病病毒(ALV-J)共感染时对彼此病毒血症及抗体反应的影响,2日龄SPF鸡分别接种REV、ALV-J或同时2种病毒造成共感染,对各感染组7周内的病毒血症及抗体反应进行动态检测。相对于单一感染,共感染时,2种病毒的病毒血症水平动态均无明显变化。在单独感染ALV-J后5周有30%(5/16)的鸡产生抗体,而有REV共感染时,没有鸡产生针对ALV-J的抗体(0/16),表明REV感染可明显抑制鸡体对ALV-J抗体的反应,而REV与ALV-J共感染对REV抗体反应无明显影响。In order to discuss the interaction of viremia and antibody caused by reticuloendotheliosis （REV） and avian leucosis virus of subgroup J（ALV-J）,REV,ALV-J and REV ＋ALV-J were injected to SPF chicken at 2 d separately, then tested the viremia and antibody dynamically for 7 weeks. The results indicated that compared with single infection, the dynamic viremia level of REV and ALV-J wasn＇t obviously different when coinfected. When only infected with ALV-J,there was 30%（5/16） chickens which occurred -the antibody of ALV-J after 5 weeks. But the positive rate of ALV-J antibody was 0 when coninfected with REV before 7 weeks. It is indicated that the emerge of ALV-J antibody was inhibitated by the coinfection of REV.although the coinfection of ALV-J didn＇t affect the emerge of antibody of REV.

关 键 词：禽网状内皮增生病病毒 禽J亚群白血病病毒 病毒血症 特异性抗体 

分 类 号：S852.65[农业科学—基础兽医学] S858.31[农业科学—兽医学]