不同方法制备姜黄素脂质体的研究  

Study on Preparing Curcumin Liposomes by Different Methods

作　　者：许汉林[1] 孙芸[1] 邵继征[1] 熊利容[1] 

机构地区：[1]湖北中医学院,湖北武汉430061

出　　处：《中国中医药信息杂志》2006年第7期51-52,共2页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的研究姜黄素脂质体制备的最佳方法。方法通过5种不同的方法制备脂质体,采用紫外可见分光光度法测定其包封率,检测波长424nm。结果乙醇注入法制备的姜黄素脂质体包封率达73.5%。结论乙醇注入法制备工艺简单,易于掌握,为提高姜黄素生物利用度提供了一种可能的新剂型。Objective To study on preparation and encapsulation of Curcumin liposomes. Method Liposome was prepared by five kinds of methods, determining the encapsulation efficiency by Visible Spectrophotomery on 424 nm. Result The envelopment ratio of Curcumin liposome made by the method of ethanol injection was 73.5%. Conclusion The preparation process of ethanol injection is simple and apt to control. The new form of prepared drug can improve bioavailability of Curcumin.

关 键 词：姜黄素 脂质体 制备工艺 

分 类 号：R283.5[医药卫生—中药学]