甘肃省汉、藏族ApoB位点遗传多态性的初步研究  

Study on Genetic Polymorphism of ApoB Locus in Han and Zang Population in Gansu Province

作　　者：何小玲[1] 王勋陵[2] 谢小冬[2] 

机构地区：[1]湛江师范学院生化学院,广东湛江524048 [2]兰州大学生命科学学院,甘肃兰州730000

出　　处：《湛江师范学院学报》2006年第3期62-65,共4页Journal of Zhanjiang Normal College

基　　金：甘肃省97重点攻关项目(GK979-2-111A)

摘　　要：用Amp-FLP分析技术对110份甘肃省汉族、93份藏族ApoB位点的等位基因进行多态性分析,建立了2个民族正常群体ApoB位点基因的遗传学参数,分析了他们在等位基因分布上的差异,并比较了他们与成都汉族之间在等位基因的数目和频率分布上的差异性.结果表明甘肃汉族与成都汉、藏族之间以及藏族与成都汉族之间都存在着显著性差异(P<0.01),支持了将现代中国人分为北部类型、南部类型和藏彝走廊类型的观点.By use of Amp-Flp technique, the allele polymorphisms of 110 Han and 93 Zang individuals in Gansu were surveyed. The genetic parameters of APOB in two ethnic healthy populations were constituted, and the difference in the number and distribution of alleles were analyzed. It showed that there exists significant difference among Han population in Gansu, Hart population in Chengdu and Zang population in Gansu （P 〈 0.01）. It supported the view that mordem Chinese people were consisted of the types of North South and the corridor of Zang-Yi.

关 键 词：ApoB位点 扩增片段多态性(Arap-Flp) 藏族 群体遗传学 

分 类 号：Q987[生物学—遗传学]