成人麻疹112例流行病学和临床特征  

The analysis of epidemiological and clinical characteristics of 112 cases patients with adult-measles

作　　者：陈小华[1] 许洁[2] 臧国庆[1] 

机构地区：[1]上海交通大学附属上海市第六人民医院感染病科,200233 [2]上海交通大学附属第三人民医院感染病科

出　　处：《中华传染病杂志》2006年第3期183-185,共3页Chinese Journal of Infectious Diseases

摘　　要：目的对2005年1月至6月上海交通大学附属第六人民医院、附属第三人民医院收治的112例成人麻疹患者临床资料进行分析,探讨本次成人麻疹流行病学特点及临床特征。方法对收治的112例麻疹患者的临床资料进行回顾性分析。结果112例患者(男63例,女49例),男女比为1．3：1,平均年龄约32岁,非上海户籍人员占40．18%,发病集中于4～5月份,血清麻疹IgM抗体阳性率为96．43%,热峰高于39℃97例(86．61%),并发麻疹病毒性肝炎36例(32．14%)。结论可能与麻疹疫苗接种不规范或接种疫苗抗体滴度下降等因素有关,临床特征具有较重的病毒血症以及肝脏损害。Objective To analyze the clinical data of 112 patients with adult-measles in the Affiliated Shanghai Sixth People＇s Hospital and Third People＇s Hospital of Shanghai Jiaotong University from January to June in 2005, and to evaluate the epidemiological and clinical characteristics of adultmeasles. Methods To retrospectively analyze the clinical data of 112 patients with adult-measles. Results Totally, 112 measles patients were involved in this study, with male 63 and female 49 respectively. The gender rate was 1.3 ： 1, average age about 32 years and the proportion of non-residents was 40.18%. The peak of the incidence of disease emerged in April and May, and the positive rate of measle virus IgM antibody in serum was 96.43%. There were 97 patients（86.61%） who had the fever that beyond 39℃ and 36 patients（32.14%） who had measle caused viral hepatitis. Conclusions There is a trend that the ages of patients that suffered from measle were postponed and the incidences of disease are increased year by year, which maybe related to the nonstandard inoculation of measle vaccine, or the decrease of IgM antibody levels and so on. Meanwhile, serious toxemic syrup toms and liver damage can be observed.

关 键 词：麻疹 临床特征 流行病学 疫苗 

分 类 号：R511.1[医药卫生—内科学]