HBsAg阳性母亲死胎肾脏组织中HBV表达  

Expression of HBV in the kidney tissues of the died fetus deliver from mother infected with HBV

作　　者：卢昆林[1] 曹清[1] 缪松毅[1] 刘立辉[1] 

机构地区：[1]解放军第180医院,福建泉州362000

出　　处：《中国优生与遗传杂志》2006年第7期57-57,共1页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨乙型肝炎病毒通过产妇传播在胎儿肾脏组织中表达的情况。方法采用我院行中期妊娠引产,HBsAg阳性产妇分娩的死胎30例。取死胎肾脏组织用SP法检测死胎肾脏组织中HBcAg。结果孕妇血清乙型肝炎标志物小三阳及大三阳分娩的死胎肾脏组织中HBcAg阳性分别为6/12(50%)及10/18(55.6%)。两者之间比较无显着性差别(P>0.05)。结论死胎肾脏组织中HBcAg阳性率与孕妇HBV标志物无关,肾脏组织可能存在HBV复制。Objective： To study the comditions in the Kidney tissues of the died fetus infected by HBV through maternal-fetul transmission. Methods： The kindney tissues of 30 died fetus infected with HBV, who were delivered during the second trimester of pregnancy, were detected HbcAg with immunocytochemistry. Results： Amony the 12 died fetus samples from the mothers with positive HBsAg. Amony the 18 died fetus samples from the mothers with positive HBsAg, HBeAg and HBcAg. There was no statistically significant （ P 〉 0. 05 ） between the two group. Conclusion： The HBcAg in the kidney was not correlated with veins. HBV mayby be copy in the kindney tissues.

关 键 词：死胎 肾脏组织 HBCAG 母婴传播 

分 类 号：R714.2[医药卫生—妇产科学]