电针对肾虚型复合应激模型大鼠脾脏形态学的影响  

Effects of electroacupuncture on morphology of spleen in compound stress rats with kidney deficiency

作　　者：马彦红[1] 孟宏[2] 辛随成[3] 图娅[3] 

机构地区：[1]中国人民解放军第305医院理疗科,北京100017 [2]中国中医研究院针灸研究所 [3]北京中医药大学针灸学院

出　　处：《中国康复医学杂志》2006年第6期488-490,500,共4页Chinese Journal of Rehabilitation Medicine

基　　金：国家中医药管理局资助项目(02-03jp05)

摘　　要：目的:观察电针对肾虚型复合应激模型大鼠脾脏光镜结构的变化,以期为CFS与免疫系统相关性提供形态学依据。方法:光镜下观察电针治疗肾虚型复合应激模型大鼠脾脏一般形态学状况,并测定脾指数,脾小体直径、中央动脉管腔直径,每组检测同时设立正常组和模型组为对照。结果:电针组、模型组、正常组光镜下形态学改变差异显著,肾虚模型组大鼠脾小体直径、中央动脉管腔直径都明显缩小,与正常组比较差异有显著性意义(P<0.05);电针组脾小体直径、中央动脉管腔直径都增加,与模型组比较差异有显著性意义(P<0.05)。结论:复合应激所致的肾虚型大鼠脾脏形态学发生了改变,电针对其有调整作用。Objective：To find a related morphology evidence for immunosystemic change of chronic fatigue syndrome （CFS）.Method：Sixty male Wistar rats were randomly assigned to blank group, model group and electroacupuncture group with 20 rats in each group. The rats in the model group and electroacupuncture group were made into models by drug withdrawal method using swimming in cold water adding adrenal cortical hormone. When models were built,those in the electroacupuncture group were treated with electroacupuncture at Baihui （GV20）,Zusanli（ST36）,Taixi （K I 3）,etc. After building models,8 rats were selected from each group randomly, and this spleens were harvested under anesthesia. Then observed spleen index, diameter of splenic nodules and central artery under high power microscope.Result：Twenty-four rats were all involved in the result analysis. ①Diameter of splenic nodules and central artery in the model group were decreased significantly than those in the blank group, and the difference had apparent significance （P〈0.05）; ②Diameter of splenic nodules and central artery in the electroacupuncture group were increased than those in the model group, and the difference had markedly significance between the two groups （P〈 0.05）.Conclusion：There was marked change on the morphology of spleen in compound stress rats with kidney deftciency.The electroacupuncture can adjust function of immune system in experimental animals, and reinforce the ability of disease prevention.

关 键 词：慢性疲劳综合征 脾 针刺 

分 类 号：R245[医药卫生—针灸推拿学]