枢星联合方案预防顺铂(DDP)致恶心呕吐的观察及护理  

Observation and nursing care on prevention of nausea and vomiting caused by DDP in using combined Shuxing regimen.

作　　者：廖春莲 刘贻娟 梁军 

机构地区：[1]农垦中心医院,广东湛江524002

出　　处：《齐鲁护理杂志》2006年第03A期385-386,共2页Journal of Qilu Nursing

摘　　要：目的：研究枢星联合方案（枢星联合地塞米松及胃复安）预防顺铂联合化疗所致恶心呕吐的疗效及护理干预。方法：将93例接受以顺铂为主联合化疗的患者随机分为两组，实验组53例接受70周期化疗并给予护理干预；对照组40例接受57周期常规化疗，观察1～5d，对两组恶心、呕吐控制率进行比较。结果：实验组对急性恶心、呕吐控制率分别为90％及94．3％，均较对照组（77．2％和80．87％）明显提高（P〈0．05）。结论：枢星联合方案结合护理干预可较好地预防顺铂所致的急性恶心、呕吐，使患者以更为舒适的状态接受化疗。Objective： To study the efficacy of combined Shuxing regimen （Shuxing, Dexamethasone and metoclopromide） in the prevention of nausea and vomiting by cisplatin and corresponding nursing intervention. Methods： 93 patients were randomized into experimental group （n = 53 ） and control group （n = 40）. 53 patients in the experimental group were given 70 cycles of chemotherapy and nursing intervention, while the other 40 patients in the control group were treated with 57 cycles of chemotherapy singly. The nausea and vomiting were observed in the first five days and compared. Results ： For controlling acute nausea and vomiting, the efficacy rate were 90% and 94.3% in the experimental group, and much improvement was seen compared with the percentage of 77.2% and 80.87% in the control group （ P 〈 0. 05 ）. Conclusion： Combined Shuxing regimen with corresponding nursing intervention can effectively prevent from nausea and vomiting and have patients comfortable when chemotherapy is processed.

关 键 词：枢星 预防 顺铂 呕吐 护理 

分 类 号：R473.5[医药卫生—护理学]