获得性免疫缺陷综合征相关消化系统疾病表现72例  

Acquired immune deficiency syndrome-related lesions in digestive system: A report of 72 cases

作　　者：梁兵[1] 黎明[1] 吴照运 贲昆龙[1] 

机构地区：[1]昆明医学院附属第一院消化内科,650032 [2]云南省大板桥园艺场医院

出　　处：《中华消化杂志》2006年第6期396-398,共3页Chinese Journal of Digestion

摘　　要：目的探索获得性免疫缺陷综合征(AIDS)患者相关消化系统疾病的发生率、临床表现、发病机制及诊断。方法对1000例共用针具静脉注射海洛因者进行问诊、体检及理化检查,按美国疾病预防控制中心CEC诊断标准筛选出CD4+T淋巴细胞<400／μl、人类免疫缺陷病毒(HIV)载量>400拷贝／ml并有消化系统损害的72例作为观察对象。结果 AIDS相关消化系统疾病发生率为1．4％- 98．6％不等,其中口咽部和胃肠道病变71例(98．6％),肝胆胰病变59例(81．9％)。主要表现为发热、腹泻、进行性消瘦、持续性全身淋巴结病、机会性感染、恶性病变、多器官多系统损害。结论 AIDS相关消化系统疾病主要由HIV直接损害、机会性感染、肿瘤及免疫病理损害所致。Objective To explore the morbidity, manifestation, pathogenesis and diagnosis of acquired immune deficiency syndrome（ AIDS）-related lesions in digestive system. Methods The complete history interview, physical examination and diagnostic test were made in a total of 1000 heroin addictors with intravenous injection. Seventy-two of them were selected as AIDS based on the diagnosis criteria on HIV/AIDS of Centers for Disease Control（CDC） （CD4＋ T cell count lower than 400/μl and human im- munodeficiency virus（HIV） load higher than 400 copies/ml）. Results Main clinical manifestations of AIDS were persistent low fever, diarrhea, progressive exhaustion, opportunistic infection, tumorgenesis and multiple organ impairment. The morbidity of AIDS-related lesions in digestive system ranged from 1.4% to 98. 6%. Oropharyngeal and gastrointestinal lesions occurred in 71 cases （98. 6%）, while hepatic, biliary and pancreatic impairment occurred in 59 cases （81.9 %）. Conclusions AIDS-related lesions in digestive system are common in AIDS patients which are mainly caused by HIV invasion, opportunistic infection, tumorgensis and immune system impairment.

关 键 词：获得性免疫缺陷综合征 消化系统疾病 临床表现 

分 类 号：R512.91[医药卫生—内科学] R57[医药卫生—临床医学]