呼吸道感染铜绿假单胞菌耐药特点分析  

Analysis of the bacterial resistance of respiratory tract infection with Pseudomons aeruginosa

作　　者：张芳[1] 尹德明[1] 车殿茹[2] 

机构地区：[1]北京市通州区潞河医院,101149 [2]北京市通州区中医医院,101149

出　　处：《医药世界》2006年第6期71-72,共2页Medicine World

摘　　要：目的分析呼吸道感染铜绿假单胞菌的耐药性,为临床用药提供参考。方法收集北京通州区2002年10月～2004年10月住院病人的各种呼吸道标本分离的铜绿假单胞菌136株,使用微量稀释法进行药敏试验,并对结果进行分析。结果136株铜绿假单胞菌敏感性最高的抗菌药物是哌拉西林/他唑巴坦(94.1%),其次分别为哌拉西林(89.7%)、亚胺硫霉素(85.3%)、头孢他啶(79.4%)、环丙沙星(77.9%)。同时耐氨苄青霉素、头孢噻肟、头孢唑啉和头孢西丁四种药的铜绿假单胞菌最多。结论铜绿假单胞菌是临床常见致病菌,耐药性严重。治疗中应根据分离株耐药特点选择合理用药方案,避免MDRP的出现。Objective To analysis the bacterial resistance of respiratory tract infection with Pseudomonas aeruginosa （PA）, and to provide reference for clinical therapy. Methods A total of 136 isolates of PA were collected from respirarory samples of patients from Octorber,2002 to Octorber, 2004.The broth microdilution test were used .The laboratory data were analysised. Results The resistance rates of PA strains to piperacillin/tazobactam ,piperacillin, imipenem,ceftazidime and ciprofloxacin were 94.1%,89.7%,85.3%,79.4% and 77.9% respectively. The most frequently resistance of PA was to ampicillin,cefotaxime,cefazolin and cefoxitin together. Conclusions The infection caused by PA is common in clinics.The problem of drug resistance is very serious.Antimicrobial agents should chosen according to the results of antimicrobial susceptibility..It is important to avoid multi drug resistant Pseudomonas aeruginosa （MDRP）.

关 键 词：铜绿假单胞菌 呼吸道感染 耐药性 

分 类 号：R521[医药卫生—内科学]