53例环状肉芽肿临床观察  

Clinical Observations of 53 cases of Granuloma Annulare

作　　者：王松[1] 沈宏[1] 王一玲[1] 施桂芬[1] 郑俊惠[1] 

机构地区：[1]浙江省杭州市第三人民医院,310009

出　　处：《医学研究杂志》2006年第7期66-67,共2页Journal of Medical Research

摘　　要：目的探讨环状肉芽肿(GA)的诱因、临床特点及组织学改变情况。方法分析53例环状肉芽肿的临床及病理资料。结果局限性肉芽肿(LGA)与泛发性肉芽肿(GGA)中部分患者病情与日晒有关,尤以后者为甚。且GGA比LGA发病年龄晚、病程长。组织学改变以栅栏状肉芽肿最常见(占71.7%),散在性组织细胞浸润次之(占28.3%)。冷冻、外用糖皮质激素多用于LGA,系统性的用药主要用于GGA。结论日照可能在泛发性环状肉芽肿中起一定作用,组织学改变以栅栏状肉芽肿最常见。LGA治疗以局部为主,GGA治疗以系统为主。Objective To speculate the precipitating factors,clinical features and histopathological changes in patients with granuloma annulare （GA）, Methods A study was performed in 53 patients with GA , Results The incidence of female was more prevalent than male in our study, The exposure of sunlight was found more relatedly in GGA than LGA, The onset age of GGA was inclined to be elder and GGA seemed to last longer. The histopathological study showed that palisading granuloma pattern accounted for 71.7% in all patients, and scattered histiocytic infiltration accounted for 28.3%, Such as cryotherapy,topical steroids were used for LGA and systemic administration was an alternative to GGA. Conclusions Ultraviolet may be associated with the development of generalized GA. The most common pattern is the palisading granuloma though the histopathological changes were variable. Topical therapy is effective in LGA,while the systemic therapy is mainly used for GGA,

关 键 词：肉芽肿 环形 组织病理 治疗 

分 类 号：R758.69[医药卫生—皮肤病学与性病学] R454.3[医药卫生—临床医学]